Literature DB >> 11520245

Cytotoxicity of Ganoderma lucidum triterpenes.

T S Wu1, L S Shi, S C Kuo.   

Abstract

Two new triterpenoids, lucidenic acid N (1) and methyl lucidenate F (2), together with four known compounds, lucidenic acid A, lucidenolactone, lucidenic acid C, and ganoderic acid E, were isolated from the dried fruiting bodies of Ganoderma lucidum. Their structures were elucidated by spectral and chemical transformation studies. Among them, lucidenic acid N (1), lucidenic acid A, and ganoderic acid E showed significant cytotoxic activity against Hep G2, Hep G2,2,15, and P-388 tumor cells.

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Year:  2001        PMID： 11520245     DOI： 10.1021/np010115w

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  14 in total

1.  Tubulin polymerization-stimulating activity of Ganoderma triterpenoids.

Authors:  Toshitaka Kohno; Tran Hai-Bang; Qinchang Zhu; Yhiya Amen; Seiichi Sakamoto; Hiroyuki Tanaka; Satoshi Morimoto; Kuniyoshi Shimizu
Journal:  J Nat Med       Date:  2017-01-11       Impact factor: 2.343

Review 2.  Misconstrued versatility of Ganoderma lucidum: a key player in multi-targeted cellular signaling.

Authors:  Balraj Singh Gill; Prateek Sharma; Raj Kumar; Sanjeev Kumar
Journal:  Tumour Biol       Date:  2015-12-30

Review 3.  The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis.

Authors:  Chia-Jui Weng; Gow-Chin Yen
Journal:  Clin Exp Metastasis       Date:  2010-05-12       Impact factor: 5.150

4.  Coprinus comatus and Ganoderma lucidum interfere with androgen receptor function in LNCaP prostate cancer cells.

Authors:  Ben-Zion Zaidman; Solomon P Wasser; Eviatar Nevo; Jamal Mahajna
Journal:  Mol Biol Rep       Date:  2007-03-13       Impact factor: 2.316

5.  Induction of apoptosis in the SW620 colon carcinoma cell line by triterpene-enriched extracts from Ganoderma lucidum through activation of caspase-3.

Authors:  Zhe Ji; Qingjiu Tang; Ruixia Hao; Jinsong Zhang; Yingjie Pan
Journal:  Oncol Lett       Date:  2011-03-21       Impact factor: 2.967

Review 6.  Applications of Herbal Medicine to Treat Autosomal Dominant Polycystic Kidney Disease.

Authors:  Guangying Shao; Shuai Zhu; Baoxue Yang
Journal:  Front Pharmacol       Date:  2021-04-27       Impact factor: 5.810

Review 7.  Traditional uses, chemical components and pharmacological activities of the genus Ganoderma P. Karst.: a review.

Authors:  Li Wang; Jie-Qing Li; Ji Zhang; Zhi-Min Li; Hong-Gao Liu; Yuan-Zhong Wang
Journal:  RSC Adv       Date:  2020-11-18       Impact factor: 4.036

8.  Ergosterol peroxide isolated from Ganoderma lucidum abolishes microRNA miR-378-mediated tumor cells on chemoresistance.

Authors:  Qing-Ping Wu; Yi-Zhen Xie; Zhaoqun Deng; Xiang-Min Li; Weining Yang; Chun-Wei Jiao; Ling Fang; Sen-Zhu Li; Hong-Hui Pan; Albert J Yee; Daniel Y Lee; Chong Li; Zhi Zhang; Jun Guo; Burton B Yang
Journal:  PLoS One       Date:  2012-08-30       Impact factor: 3.240

9.  Anticancer activity of Amauroderma rude.

Authors:  Chunwei Jiao; Yi-Zhen Xie; Xiangling Yang; Haoran Li; Xiang-Min Li; Hong-Hui Pan; Mian-Hua Cai; Hua-Mei Zhong; Burton B Yang
Journal:  PLoS One       Date:  2013-06-20       Impact factor: 3.240

10.  Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs.

Authors:  A Berger; D Rein; E Kratky; I Monnard; H Hajjaj; I Meirim; C Piguet-Welsch; J Hauser; K Mace; P Niederberger
Journal:  Lipids Health Dis       Date:  2004-02-18       Impact factor: 3.876
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