Literature DB >> 1151960

Carbon-13 magnetic resonance spectroscopy of drugs. Sulfonamides.

C Chang, H G Floss, G E Peck.   

Abstract

The natural abundance 13C magnetic resonance spectra of a series of sulfonamide drugs(sulfanilamide, sulfaguanidine,sulfathiazole, sulfasuxidine, sulfadiazine, sulfamerazine, sulfamethiazine, and sulfapyridine) have been determined at 25.15 MHz employing the pulse Fourier transform technique. The chemical shefts have been assigned with the aid of off-resonance and selective proton decoupling techniques, as well as by long-range carbon-13 proton coupling patterns.

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Year:  1975        PMID: 1151960     DOI: 10.1021/jm00239a014

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


  2 in total

1.  Synthesis, physical properties and microbiological activities of more water soluble silver sulfadiazine derivatives.

Authors:  P P De Wit; H Van Doorne; A Bult
Journal:  Pharm Weekbl Sci       Date:  1983-12-16

2.  Distinction between the tautomeric forms of sulfanilamide derivatives by 13C-NMR.

Authors:  A Bult
Journal:  Pharm Weekbl Sci       Date:  1983-04-29
  2 in total

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