Literature DB >> 11518650

Synthesis and properties of 18F-labeled potential myocardial blood flow tracers.

A R Studenov1, M S Berridge.   

Abstract

PET centers without particle accelerators make clinical PET widely available at reduced cost. For myocardial perfusion tracers, these satellite PET centers are limited to generator- produced 82Rb(+) and 62Cu[PTSM]. Their limitations motivate a search for transportable alternatives. In search of new tracers we have synthesized several 18F-labeled amines and quaternary ammonium salts. Among them, 4-[18F]fluorotri-N-methylanilinium ([18F]FTMA) has flow-tracing properties. The compound is functional, but has properties that justify a continued search.

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Year:  2001        PMID： 11518650     DOI： 10.1016/s0969-8051(01)00233-5

Source DB:  PubMed          Journal:  Nucl Med Biol        ISSN： 0969-8051            Impact factor:   2.408


  9 in total

1.  Novel and simple carbon-11-labeled ammonium salts as PET agents for myocardial perfusion imaging.

Authors:  Ohad Ilovich; Hana Billauer; Sharon Dotan; Nanette M T Freedman; Moshe Bocher; Eyal Mishani
Journal:  Mol Imaging Biol       Date:  2011-02       Impact factor: 3.488

2.  Biodistribution and stability studies of [18F]fluoroethylrhodamine B, a potential PET myocardial perfusion agent.

Authors:  Vijay Gottumukkala; Tobias K Heinrich; Amanda Baker; Patricia Dunning; Frederic H Fahey; S Ted Treves; Alan B Packard
Journal:  Nucl Med Biol       Date:  2010-02-10       Impact factor: 2.408

3.  (18)F-labeled rhodamines as potential myocardial perfusion agents: comparison of pharmacokinetic properties of several rhodamines.

Authors:  Mark D Bartholomä; Shaohui Zhang; Vamsidhar Akurathi; Christina A Pacak; Patricia Dunning; Frederic H Fahey; Douglas B Cowan; S Ted Treves; Alan B Packard
Journal:  Nucl Med Biol       Date:  2015-06-18       Impact factor: 2.408

4.  Syntheses of 11C- and 18F-labeled carboxylic esters within a hydrodynamically-driven micro-reactor.

Authors:  Shui-Yu Lu; Paul Watts; Frederick T Chin; Jinsoo Hong; John L Musachio; Emmanuelle Briard; Victor W Pike
Journal:  Lab Chip       Date:  2004-09-28       Impact factor: 6.799

5.  Synthesis and evaluation of two 18F-labeled 6-iodo-2-(4'-N,N-dimethylamino)phenylimidazo[1,2-a]pyridine derivatives as prospective radioligands for beta-amyloid in Alzheimer's disease.

Authors:  Lisheng Cai; Frederick T Chin; Victor W Pike; Hiroshi Toyama; Jeih-San Liow; Sami S Zoghbi; Kendra Modell; Emmanuelle Briard; H Umesha Shetty; Kathryn Sinclair; Sean Donohue; Dnyanesh Tipre; Mei-Ping Kung; Claudio Dagostin; David A Widdowson; Michael Green; Weiyi Gao; Mary M Herman; Masanori Ichise; Robert B Innis
Journal:  J Med Chem       Date:  2004-04-22       Impact factor: 7.446

6.  Synthesis of fluorine-18 labeled rhodamine B: A potential PET myocardial perfusion imaging agent.

Authors:  Tobias K Heinrich; Vijay Gottumukkala; Erin Snay; Patricia Dunning; Frederic H Fahey; S Ted Treves; Alan B Packard
Journal:  Appl Radiat Isot       Date:  2009-08-28       Impact factor: 1.513

7.  Effect of the prosthetic group on the pharmacologic properties of 18F-labeled rhodamine B, a potential myocardial perfusion agent for positron emission tomography (PET).

Authors:  Mark D Bartholomä; Vijay Gottumukkala; Shaohui Zhang; Amanda Baker; Patricia Dunning; Frederic H Fahey; S Ted Treves; Alan B Packard
Journal:  J Med Chem       Date:  2012-12-14       Impact factor: 7.446

8.  The synthesis of 18F-FDS and its potential application in molecular imaging.

Authors:  Zi-Bo Li; Zhanhong Wu; Qizhen Cao; David W Dick; Jeffrey R Tseng; Sanjiv S Gambhir; Xiaoyuan Chen
Journal:  Mol Imaging Biol       Date:  2007-12-21       Impact factor: 3.488

Review 9.  Research Progress on 18F-Labeled Agents for Imaging of Myocardial Perfusion with Positron Emission Tomography.

Authors:  Tiantian Mou; Xianzhong Zhang
Journal:  Molecules       Date:  2017-03-30       Impact factor: 4.411
  9 in total

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