| Literature DB >> 11517413 |
C L Cubitt1, X Cui, H T Agostini, V R Nerurkar, I Scheirich, R Yanagihara, C F Ryschkewitsch, G L Stoner.
Abstract
DNA sequence variation between JCV genotypes is confined largely to noncoding intergenic regions and introns. Nevertheless, evidence suggests that the amino acid sequence variations among the 8 genotypes of JCV can influence the potential for neurovirulence of the virus. In the current study, the amino acid sequences for 100 JCV genomes were translated and grouped into genotype families. Subtype consensus sequences were determined and the type-specific amino acid sequence variants were identified.Mesh:
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Year: 2001 PMID: 11517413 DOI: 10.1080/13550280152537201
Source DB: PubMed Journal: J Neurovirol ISSN: 1355-0284 Impact factor: 2.643