Literature DB >> 115172

Increased responsiveness of electric precipitation (electrosynerese) by means of a chemical method.

S Ottó, R Verzár, E Somogyi.   

Abstract

Electric precipitation is a method in serological diagnostics (determination of species-specificity). Since serum protein fractions (especially immunoglobulins) and extracts from blood stains migrate in agar-gel at pH 8.2--8.6 towards the cathode they cannot be used for the determination of the species specificity. By a chemical method using glutaraldehyde authors have produced an albumin-immunoglobulin complex, altering in this way the direction of electrophoretic mobility. Treatment of the blood samples with glutaraldehyde increases the sensitivity and realiability of the method.

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Year:  1979        PMID: 115172     DOI: 10.1007/bf02092265

Source DB:  PubMed          Journal:  Z Rechtsmed        ISSN: 0044-3433


  4 in total

1.  PRECIPITIN REACTIONS IN FORENSIC PROBLEMS. A NEW METHOD FOR PRECIPITIN REACTIONS ON FORENSIC BLOOD, SEMEN AND SALIVA STAINS.

Authors:  B J CULLIFORD
Journal:  Nature       Date:  1964-03-14       Impact factor: 49.962

2.  [Description of a technic simultaneously combining electrophoresis and immunological precipitation in gel: electrosyneresis].

Authors:  A BUSSARD
Journal:  Biochim Biophys Acta       Date:  1959-07

3.  The medico-legal importance of immunological cross reactions.

Authors:  S Ottó; E Somogyi
Journal:  Z Rechtsmed       Date:  1974-06-18

4.  Electroimmunoquantitation of serum proteins cross-linked by glutaraldehyde.

Authors:  K Lou; J Bowers
Journal:  J Immunol Methods       Date:  1975-11       Impact factor: 2.303

  4 in total

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