Literature DB >> 11517135

Identification of polysubstance abuse in the parturient.

D J Birnbach1, I M Browne, A Kim, D J Stein, D M Thys.   

Abstract

Illicit drugs are widely used by inner city patients and their use by pregnant women has increased in recent years. The aim of this study was to determine the prevalence of polysubstance abuse among parturients at our institution who received no prenatal care ('unbooked') and to determine the accuracy of the Ontrak TesTcup an in vitro immunodiagnostic assay. We prospectively analysed urine from 50 'unbooked' parturients and found that 26 (52%) tested positive for cocaine. Of these, six patients (23%) were also positive for morphine. All TesTcup results were confirmed by the hospital laboratory using alternate chemical methods. When comparing TesTcup to the hospital laboratory, there were no false positive or negative results. Given the high frequency of concomitant opioid abuse in cocaine-abusing parturients, anyone suspected of cocaine abuse should be tested for other illicit substances. TesTcup is a clinically accurate test that allows the rapid assessment of several drugs of abuse, which may impact on anaesthetic care.

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Mesh:

Substances:

Year:  2001        PMID: 11517135     DOI: 10.1093/bja/87.3.488

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  4 in total

1.  A developmental origins perspective on the emergence of violent behavior in males with prenatal substance exposure.

Authors:  Sarah Terrell; Elisabeth Conradt; Lynne Dansereau; Linda Lagasse; Barry Lester
Journal:  Infant Ment Health J       Date:  2018-12-21

Review 2.  Treatment of cocaine abuse during pregnancy: translating research to clinical practice.

Authors:  Lynn Hull; James May; Dawn Farrell-Moore; Dace S Svikis
Journal:  Curr Psychiatry Rep       Date:  2010-10       Impact factor: 5.285

3.  Mental and behavioral disorders due to substance abuse and perinatal outcomes: a study based on linked population data in New South Wales, Australia.

Authors:  Michelle R Bonello; Fenglian Xu; Zhuoyang Li; Lucy Burns; Marie-Paule Austin; Elizabeth A Sullivan
Journal:  Int J Environ Res Public Health       Date:  2014-05-08       Impact factor: 3.390

Review 4.  Neuroendocrine and immune pathways from pre- and perinatal stress to substance abuse.

Authors:  Sarah R Horn; Leslie E Roos; Elliot T Berkman; Philip A Fisher
Journal:  Neurobiol Stress       Date:  2018-09-17
  4 in total

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