Literature DB >> 1151712

High-pressure liquid chromatographic analysis of penicillin G potassium and its degradation products.

J M Blaha, A M Knevel, S L Hem.   

Abstract

An anion-exchange high-pressure liquid chromatographic system capable of separating penicillin G potassium from five of its degradation products was developed. The retention times were: penicillin G potassium, 17.5 min; DL-penicillamine, 4.5 min; benzylpenilloic acid, 7.0 and 8.0 min; benzylpenamaldic acid, 13.0 min; benzylpenicilloic acid, 19.5 min; and benzylpenillic acid, 22.0 min. In addition, the system permits quantification using linear calibration curves.

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Year:  1975        PMID: 1151712     DOI: 10.1002/jps.2600640827

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN: 0022-3549            Impact factor:   3.534


  1 in total

1.  Utilization of benzylpenicillin as carbon, nitrogen and energy source by a Pseudomonas fluorescens strain.

Authors:  J Johnsen
Journal:  Arch Microbiol       Date:  1977-12-15       Impact factor: 2.552

  1 in total

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