Literature DB >> 11516564

Continual replacement of newly-generated olfactory neurons in adult rats.

T Kato1, K Yokouchi, N Fukushima, K Kawagishi, Z Li, T Moriizumi.   

Abstract

It has been known that stem cells do exist in the central nervous system, and adult neurogenesis is continually taking place in the olfactory bulb during life. We report here, with the combined method of autoradiography using (3)H-thymidine and immunohistochemistry for a neuronal marker, that 65.3-76.9% of calretinin-immunoreactive bulbar neurons are replaced during the short period of 6 weeks in the adult rodent. The results indicate that neuronal replacement is a common phenomenon in the olfactory bulb during life.

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Year:  2001        PMID: 11516564     DOI: 10.1016/s0304-3940(01)01914-0

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN: 0304-3940            Impact factor:   3.046


  6 in total

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