Literature DB >> 11516081

Polymeric microspheres composed of pH/temperature-sensitive polymer complex.

E J Kim1, S H Cho, S H Yuk.   

Abstract

A new pH/temperature-sensitive polymer system with transitions resulting both from polymer-water and polymer-polymer interactions has been demonstrated using the mixture of poly(N,N-dimethylamino)ethyl methacrylate (DMAEMA) and polyethyl acrylamide (EAAm). Based on the pH/temperature sensitivity of polymer mixture, the microsphere for pH/temperature-sensitive drug release have been designed and characterized. Hydrocortisone was used as a model drug. This gave the control of hydrocortisone release in an on-off manner without considerable lag time.

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Year:  2001        PMID： 11516081     DOI： 10.1016/s0142-9612(00)00439-7

Source DB:  PubMed          Journal:  Biomaterials        ISSN： 0142-9612            Impact factor:   12.479


  4 in total

Review 1.  The use of micro- and nanospheres as functional components for bone tissue regeneration.

Authors:  Huanan Wang; Sander C G Leeuwenburgh; Yubao Li; John A Jansen
Journal:  Tissue Eng Part B Rev       Date:  2011-09-23       Impact factor: 6.389

2.  Calcium alginate/dextran methacrylate IPN beads as protecting carriers for protein delivery.

Authors:  Giorgia D'Arrigo; Chiara Di Meo; Laura Pescosolido; Tommasina Coviello; Franco Alhaique; Pietro Matricardi
Journal:  J Mater Sci Mater Med       Date:  2012-04-24       Impact factor: 3.896

3.  Morphology and release kinetics of protein-loaded porous poly(l-lactic Acid) spheres prepared by freeze-drying technique.

Authors:  Takashi Sasaki; Kazuki Tanaka; Daisuke Morino; Kensuke Sakurai
Journal:  ISRN Pharm       Date:  2011-08-15

Review 4.  Nanomaterials-Tools, Technology and Methodology of Nanotechnology Based Biomedical Systems for Diagnostics and Therapy.

Authors:  Christian Schmidt; Joachim Storsberg
Journal:  Biomedicines       Date:  2015-07-20
  4 in total

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