Literature DB >> 11514158

Synthesis of OSW-1 analogues and a dimer and their antitumor activities.

X Ma1, B Yu, Y Hui, Z Miao, J Ding.   

Abstract

Five analogues, including a 16-epi-isomer (6), and a 3-terephthalic acid linked dimer (8) of OSW-1 were synthesized. Their inhibitory activities on P388 and A-549 cells were detected.

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Year:  2001        PMID： 11514158     DOI： 10.1016/s0960-894x(01)00389-4

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  4 in total

1.  A total synthesis of OSW-1.

Authors:  Jie Xue; Peng Liu; Yanbin Pan; Zhongwu Guo
Journal:  J Org Chem       Date:  2007-12-08       Impact factor: 4.354

2.  Discovery of SBF1 as an allosteric inhibitor targeting the PIF-pocket of 3-phosphoinositide-dependent protein kinase-1.

Authors:  Wei Liu; Pengfei Li; Ye Mei
Journal:  J Mol Model       Date:  2019-06-13       Impact factor: 1.810

Review 3.  Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds.

Authors:  Gang Chen; Feng Wang; Dunyaporn Trachootham; Peng Huang
Journal:  Mitochondrion       Date:  2010-08-14       Impact factor: 4.160

4.  Effective killing of leukemia cells by the natural product OSW-1 through disruption of cellular calcium homeostasis.

Authors:  Celia Garcia-Prieto; Kausar Begam Riaz Ahmed; Zhao Chen; Yan Zhou; Naima Hammoudi; Ying Kang; Changgang Lou; Yan Mei; Zhendong Jin; Peng Huang
Journal:  J Biol Chem       Date:  2012-12-17       Impact factor: 5.157
  4 in total

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