Literature DB >> 11513181

A prospective cohort study of practice guidelines in inflammatory bowel disease.

W J Tremaine1, W J Sandborn, E V Loftus, M L Kenan, T M Petterson, A R Zinsmeister, M D Silverstein.   

Abstract

OBJECTIVES: Practice guidelines should improve care, but they are not routinely followed, in part because of lack of proven benefit. We evaluated the effect of introducing guidelines for inflammatory bowel disease (IBD) on practice variation and the IBD Quality of Life (IBDQ) score.
METHODS: This was a prospective, controlled, cohort study. A total of 65 patients were matched according to month of visit, diagnosis, and disease activity with control subjects seen 1 yr earlier. Physicians were educated throughout the study regarding the guidelines. Variation was measured by the Mayo Practice Guideline Score (MPGS), a 15-point assessment of documentation of diagnosis, nutrition, social support, education, functional status, and treatment. The IBDQ was measured at baseline and at 1 yr in the intervention group and after 1 yr in the control group.
RESULTS: The MPGS was significantly higher in the intervention group compared to the controls (p = 0.002), with median values of 12 versus 11. The IBDQ median score increased significantly in the intervention group (p < 0.001), baseline median of 133 versus 15-month median of 184. However, the final IBDQ was not significantly higher in the intervention group than in the controls (p = 0.33).
CONCLUSIONS: Practice guidelines for IBD reduce practice variation. The quality of life improved significantly compared to baseline with practice guidelines, but not compared to controls, perhaps because of the small sample size and homogenous practice setting. The MPGS is a tool that can be used in day-to-day management of IBD patients.

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Mesh:

Year:  2001        PMID: 11513181     DOI: 10.1111/j.1572-0241.2001.04042.x

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  5 in total

Review 1.  Quality of care in inflammatory bowel disease.

Authors:  Brijen Shah; Andrew Tinsley; Thomas Ullman
Journal:  Curr Gastroenterol Rep       Date:  2011-02

Review 2.  Gastroenterology services in the UK. The burden of disease, and the organisation and delivery of services for gastrointestinal and liver disorders: a review of the evidence.

Authors:  J G Williams; S E Roberts; M F Ali; W Y Cheung; D R Cohen; G Demery; A Edwards; M Greer; M D Hellier; H A Hutchings; B Ip; M F Longo; I T Russell; H A Snooks; J C Williams
Journal:  Gut       Date:  2007-02       Impact factor: 23.059

Review 3.  Quality of health care in the United States: implications for pediatric inflammatory bowel disease.

Authors:  Brendan M Boyle; Lena Palmer; Michael D Kappelman
Journal:  J Pediatr Gastroenterol Nutr       Date:  2009-09       Impact factor: 2.839

4.  Systematic Information to Health-Care Professionals about Vaccination Guidelines Improves Adherence in Patients With Inflammatory Bowel Disease in Anti-TNFα Therapy.

Authors:  Katrine R Christensen; Casper Steenholdt; Sine S Buhl; Mark A Ainsworth; Ole Ø Thomsen; Jørn Brynskov
Journal:  Am J Gastroenterol       Date:  2015-06-02       Impact factor: 10.864

Review 5.  Budesonide (Entocort EC Capsules): a review of its therapeutic use in the management of active Crohn's disease in adults.

Authors:  Kate McKeage; Karen L Goa
Journal:  Drugs       Date:  2002       Impact factor: 9.546

  5 in total

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