Literature DB >> 11512272

Synthesis of 3-nitrosoimidazo[1,2-a]pyridine derivatives as potential antiretroviral agents.

A Chaouni-Benabdallah1, C Galtier, H Allouchi, A Kherbeche, J C Debouzy, J C Teulade, O Chavignon, M Witvrouw, C Pannecouque, J Balzarini, E de Clercq, C Enguehard, A Gueiffier.   

Abstract

Ten 2-aryl or heteroaryl-3-nitrosoimidazo[1,2-a]pyridine derivatives were synthesised as potential antiretroviral agents. The new compounds were characterized by elemental analysis, 1H NMR, and by crystallography for (14). The compounds were devoid of any activity against HIV-1 or HIV-2.

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Year:  2001        PMID： 11512272     DOI： 10.1002/1521-4184(200107)334:7<224::aid-ardp224>3.0.co;2-7

Source DB:  PubMed          Journal:  Arch Pharm (Weinheim)        ISSN： 0365-6233            Impact factor:   3.751


  2 in total

1.  4'-Methyl-3-(4-nitro-phen-yl)-4-phenyl-4,5,1',2',3',4'-hexa-hydro-spiro-[isoxazole-5,2'-naphthalen]-1'-one.

Authors:  Ghali Alhouari; Abdelali Kerbal; Najib Ben Larbi; Brahim Bennani; Taibi Ben Hadda; Helen Stoeckli-Evans
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-01-23

2.  Intramolecular H-bonding interaction in angular 3-π-EWG substituted imidazo[1,2-a]pyridines contributes to conformational preference.

Authors:  Manuel Velázquez-Ponce; Héctor Salgado-Zamora; Hugo A Jiménez-Vázquez; Maria Elena Campos-Aldrete; Rogelio Jiménez; Humberto Cervantes; Taibi Ben Hadda
Journal:  Chem Cent J       Date:  2013-01-31       Impact factor: 4.215
  2 in total

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