Literature DB >> 11512000

Herpes simplex encephalitis: MRI findings in two cases confirmed by polymerase chain reaction assay.

J W Lee1, I O Kim, W S Kim, K M Yeon, H J Lee, Y S Hwang.   

Abstract

Herpes simplex virus (HSV) type I causes a fulminant necrotising meningoencephalitis distinguished from other encephalitides by its focal and often haemorrhagic nature. Specific antiviral therapy with acyclovir can significantly improve the prognosis. We present MRI findings of two cases of herpes simplex encephalitis (HSE) confirmed by PCR analysis, focusing on the serial changes after acyclovir therapy: gyral swelling, high signal intensity on T2-weighted images in the subfrontal region, temporal lobe and insula in the initial stage, then regional extension with enhancement and haemorrhage despite appropriate acyclovir therapy, and finally encephalomalacia and brain atrophy.

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Year:  2001        PMID： 11512000     DOI： 10.1007/s002470100508

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN： 0301-0449


  3 in total

1.  Status epilepticus as a risk factor for postencephalitic parenchyma loss evaluated by ventricle brain ratio measurement on MR imaging.

Authors:  E K Herrmann; K Hahn; C Kratzer; I von Seggern; C Zimmer; E Schielke
Journal:  AJNR Am J Neuroradiol       Date:  2006 Jun-Jul       Impact factor: 3.825

2.  Herpes simplex encephalitis with two false-negative cerebrospinal fluid PCR tests and review of negative PCR results in the clinical setting.

Authors:  Adam C Adler; Srinath Kadimi; Catherine Apaloo; Corina Marcu
Journal:  Case Rep Neurol       Date:  2011-08-04

3.  Cerebrovascular manifestations of herpes simplex virus infection of the central nervous system: a systematic review.

Authors:  Larissa Hauer; Slaven Pikija; Eva C Schulte; Laszlo K Sztriha; Raffaele Nardone; Johann Sellner
Journal:  J Neuroinflammation       Date:  2019-01-29       Impact factor: 8.322
  3 in total

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