Literature DB >> 11510911

The contribution of vitamin C to healing of experimental fractures.

C Yilmaz1, E Erdemli, H Selek, H Kinik, M Arikan, B Erdemli.   

Abstract

The benefits of various minerals and vitamins on fracture healing have been demonstrated in animal models. Vitamin C is an essential substance in fracture healing but has not been studied previously on an experimental basis. Sixteen rats were grouped randomly into control and vitamin C-supplemented groups. The right tibias of all rats were fractured by digital manipulation. One group received single high dose of vitamin C intramuscularly. On the 5th, 10th, 15th, and 20th days, two rats from each group were killed and the tibias examined under light microscopy. It was seen that the vitamin C-supplemented group went through the stages of fracture healing faster compared with the control group.

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Year:  2001        PMID： 11510911     DOI： 10.1007/s004020100272

Source DB:  PubMed          Journal:  Arch Orthop Trauma Surg        ISSN： 0936-8051            Impact factor:   3.067


  11 in total

1.  Effect of vitamin C on bone formation in the expanded inter-premaxillary suture. Early bone changes.

Authors:  Tancan Uysal; Mihri Amasyali; Huseyin Olmez; Sukru Enhos; Yildirim Karslioglu; Omer Gunhan
Journal:  J Orofac Orthop       Date:  2011-08       Impact factor: 1.938

Review 2.  Testing the validity of preventing chronic regional pain syndrome with vitamin C after distal radius fracture. [Corrected].

Authors:  Sunitha Malay; Kevin C Chung
Journal:  J Hand Surg Am       Date:  2014-09-16       Impact factor: 2.230

3.  Protective effect of total and supplemental vitamin C intake on the risk of hip fracture--a 17-year follow-up from the Framingham Osteoporosis Study.

Authors:  S Sahni; M T Hannan; D Gagnon; J Blumberg; L A Cupples; D P Kiel; K L Tucker
Journal:  Osteoporos Int       Date:  2009-04-04       Impact factor: 4.507

4.  Supplementary vitamin C does not accelerate bone healing in a rat tibia fracture model.

Authors:  Vincenzo Giordano; Rodrigo Pires E Albuquerque; Ney Pecegueiro do Amaral; Cristiano Curcio Chame; Fabio de Souza; Mara Íbis Rodrigues Apfel
Journal:  Acta Ortop Bras       Date:  2012       Impact factor: 0.513

5.  Effect of alpha-tocopherol on bone formation during distraction osteogenesis: a rabbit model.

Authors:  Mustafa Kurklu; Cemil Yildiz; Ozkan Kose; Yuksel Yurttas; Ozgur Karacalioglu; Muhittin Serdar; Salih Deveci
Journal:  J Orthop Traumatol       Date:  2011-07-15

Review 6.  Understanding Reactive Oxygen Species in Bone Regeneration: A Glance at Potential Therapeutics and Bioengineering Applications.

Authors:  Aaron J Sheppard; Ann Marie Barfield; Shane Barton; Yufeng Dong
Journal:  Front Bioeng Biotechnol       Date:  2022-02-07

7.  Clinical effect of vitamin C supplementation on bone healing: A systematic review.

Authors:  K Barrios-Garay; J Toledano-Serrabona; C Gay-Escoda; M-Á Sánchez-Garcés
Journal:  Med Oral Patol Oral Cir Bucal       Date:  2022-05-01

8.  Influence of vitamin C on the incidence of CRPS-I after subacromial shoulder surgery.

Authors:  P Laumonerie; M Martel; M E Tibbo; V Azoulay; P Mansat; N Bonnevialle
Journal:  Eur J Orthop Surg Traumatol       Date:  2019-09-20

Review 9.  Efficacy of Vitamin C Supplementation on Collagen Synthesis and Oxidative Stress After Musculoskeletal Injuries: A Systematic Review.

Authors:  Nicholas N DePhillipo; Zachary S Aman; Mitchell I Kennedy; J P Begley; Gilbert Moatshe; Robert F LaPrade
Journal:  Orthop J Sports Med       Date:  2018-10-25

10.  Preoperative Ascorbic Acid Levels in Proximal Femur Fracture Patients Have No Postoperative Clinical Impact, While Ascorbic Acid Levels upon Discharge Have a Major Effect on Postoperative Outcome.

Authors:  Katharina Hill-Mündel; Johannes Schlegl; Hans Konrad Biesalski; Sabrina Ehnert; Steffen Schröter; Christian Bahrs; Donatus Nohr; Andreas K Nüssler; Christoph Ihle
Journal:  J Clin Med       Date:  2019-12-26       Impact factor: 4.241
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