Literature DB >> 11510773

Symptoms of gastroesophageal reflux disease, perceived productivity, and health-related quality of life.

P Wahlqvist1.   

Abstract

OBJECTIVES: To investigate to what extent patients consulting a general practitioner (GP) because of symptoms of gastroesophageal reflux disease (GERD) report impaired health-related quality of life, absence from work, reduced productivity while at work, and reduced daily activities.
METHODS: A disease specific, self-administered work productivity and activity impairment questionnaire (WPAI-GERD) was distributed together with a GERD-specific quality of life questionnaire (QOLRAD) and a generic questionnaire (SF-36) to a Swedish working population (N = 136) consulting a GP because of current or recent symptoms of heartburn. The severity and frequency of GERD symptoms (heartburn and acid regurgitation) were recorded by the GP.
RESULTS: Among patients with heartburn symptoms, a mean of 2.5 h absence from work per week was reported. Furthermore, productivity while working was reduced by 23% and productivity while doing regular daily activities by 30%. This corresponds to an average of 10.7 h lost from work per patient and week, of which 8.3 h are due to reduced productivity while working (23% reduction times the actual work time). Results from the quality of life questionnaires showed a poor quality of life, especially in patients with moderate to severe heartburn symptoms.
CONCLUSIONS: In patients consulting a GP because of GERD, results indicated that symptoms incur a large burden to the patient as well as a considerable cost to society due to absence from work, reduced productivity while working, and reductions of regular daily activities.

Entities:  

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Year:  2001        PMID: 11510773     DOI: 10.1016/s0002-9270(01)02590-4

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


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6.  Esomeprazole: a review of its use in the management of acid-related disorders in the US.

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Review 10.  Esomeprazole: a review of its use in the management of acid-related disorders.

Authors:  Lesley J Scott; Christopher J Dunn; Gordon Mallarkey; Miriam Sharpe
Journal:  Drugs       Date:  2002       Impact factor: 9.546

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