Literature DB >> 11509613

Identification, cloning, and recombinant expression of procalin, a major triatomine allergen.

C D Paddock1, J H McKerrow, E Hansell, K W Foreman, I Hsieh, N Marshall.   

Abstract

Among the most frequent anaphylactic reactions to insects are those attributed to reduviid bugs. We report the purification and identification of the major salivary allergen of these insects. This 20-kDa protein (procalin) is a member of the lipocalin family, which includes salivary allergens from other invertebrates and mammals. An expression system capable of producing reagent quantities of recombinant allergen was developed in Saccharomyces cerevisiae. Antisera produced against recombinant protein cross-reacts with ELISA with salivary allergen. Recombinant Ag is also shown to react with sera from an allergic patient but not with control sera. By immunolocalization, the source of the salivary Ag is the salivary gland epithelium and its secretions.

Entities:  

Mesh：

Substances：

Year:  2001        PMID： 11509613     DOI： 10.4049/jimmunol.167.5.2694

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  27 in total

1.  An insight into the sialome of the blood-sucking bug Triatoma infestans, a vector of Chagas' disease.

Authors:  Teresa C F Assumpção; Ivo M B Francischetti; John F Andersen; Alexandra Schwarz; Jaime M Santana; José M C Ribeiro
Journal:  Insect Biochem Mol Biol       Date:  2007-11-17       Impact factor: 4.714

2.  Animal lipocalin allergens.

Authors:  Christiane Hilger; Annette Kuehn; Francois Hentges
Journal:  Curr Allergy Asthma Rep       Date:  2012-10       Impact factor: 4.806

3.  Seventeen-year-old girl hospitalized for localized swelling, pruritus, tenderness, and lymphatic streaking with eosinophilia.

Authors:  Joshua L Kennedy; Susanne K Jeffus; Thomas A E Platts-Mills; Anubha Tripathi; Adnan Divjan; Matthew S Perzanowski; Peter W Heymann
Journal:  J Allergy Clin Immunol Pract       Date:  2013-02-28

4.  Insight into the salivary transcriptome and proteome of Dipetalogaster maxima.

Authors:  Teresa C F Assumpção; Sébastien Charneau; Paula B M Santiago; Ivo M B Francischetti; Zhaojing Meng; Carla N Araújo; Van M Pham; Rayner M L Queiroz; Cleudson Nery de Castro; Carlos André Ricart; Jaime M Santana; José M C Ribeiro
Journal:  J Proteome Res       Date:  2011-01-04       Impact factor: 4.466

5.  Exploring the molecular complexity of Triatoma dimidiata sialome.

Authors:  Paula Beatriz Santiago; Carla Nunes de Araújo; Sébastien Charneau; Izabela Marques Dourado Bastos; Teresa Cristina F Assumpção; Rayner Myr Lauterjung Queiroz; Yanna Reis Praça; Thuany de Moura Cordeiro; Carlos Henrique Saraiva Garcia; Ionizete Garcia da Silva; Tainá Raiol; Flávia Nader Motta; João Victor de Araújo Oliveira; Marcelo Valle de Sousa; José Marcos C Ribeiro; Jaime Martins de Santana
Journal:  J Proteomics       Date:  2017-12-27       Impact factor: 4.044

6.  Triplatin, a platelet aggregation inhibitor from the salivary gland of the triatomine vector of Chagas disease, binds to TXA(2) but does not interact with glycoprotein PVI.

Authors:  Dongying Ma; Teresa C F Assumpção; Yuan Li; John F Andersen; José Ribeiro; Ivo M B Francischetti
Journal:  Thromb Haemost       Date:  2011-12-08       Impact factor: 5.249

7.  Dipetalodipin, a novel multifunctional salivary lipocalin that inhibits platelet aggregation, vasoconstriction, and angiogenesis through unique binding specificity for TXA2, PGF2alpha, and 15(S)-HETE.

Authors:  Teresa C F Assumpção; Patricia H Alvarenga; José M C Ribeiro; John F Andersen; Ivo M B Francischetti
Journal:  J Biol Chem       Date:  2010-10-02       Impact factor: 5.157

8.  An insight into the sialotranscriptome of Triatoma rubida (Hemiptera: Heteroptera).

Authors:  José M C Ribeiro; Teresa C F Assumpção; Van M Pham; Ivo M B Francischetti; Carolina E Reisenman
Journal:  J Med Entomol       Date:  2012-05       Impact factor: 2.278

9.  A repertoire of the dominant transcripts from the salivary glands of the blood-sucking bug, Triatoma dimidiata, a vector of Chagas disease.

Authors:  Hirotomo Kato; Ryan C Jochim; Eduardo A Gomez; Ryo Sakoda; Hiroyuki Iwata; Jesus G Valenzuela; Yoshihisa Hashiguchi
Journal:  Infect Genet Evol       Date:  2009-11-10       Impact factor: 3.342

10.  The sialotranscriptome of the blood-sucking bug Triatoma brasiliensis (Hemiptera, Triatominae).

Authors:  Adriana Santos; José Marcos C Ribeiro; Michael J Lehane; Nelder Figueiredo Gontijo; Artur Botelho Veloso; Mauricio R V Sant'Anna; Ricardo Nascimento Araujo; Edmundo C Grisard; Marcos Horácio Pereira
Journal:  Insect Biochem Mol Biol       Date:  2007-04-14       Impact factor: 4.714
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.