Biometrics of reversal learning in mice: III. complete reciprocated Mendelian analysis.

A total of 118 subjects, divided into high scoring 129/J and low scoring DBA/1J parents, F2, and reciprocated F1, B1, and B2 generations, were given reversal training for 50 sessions. Results showed that the parent strain providing genes that were more favorable to reversal learning provided a maternal environment that was significantly less favorable than that provided by the other parent strain. There was also found to be significant nonalletic interaction, a genetic factor the presence of which had not been suggested by the results of earlier work using the diallel cross method.