Literature DB >> 11508625

Zn concentration in thyroid tissue and whole blood of women with different diseases of thyroid.

U Majewska1, J Braziewicz, D Banaś, A Kubala-Kukuś, M Kucharzewski, J Waler, S Góźdź, J Wudarczyk.   

Abstract

The Zn concentration in thyroid tissue and whole blood of patients with Graves' disease, thyroid cancer, and nodular goiter disease was determined using the total-reflection X-ray fluorescence method. The dependence of obtained concentrations on the clinical stage of the examined disease, histopathological grading, and kind of analyzed material (thyroid tissue and blood) was studied. The determined concentration of Zn was the lowest in the thyroid tissue of patients with thyroid cancer (23.1 microg/g) and it was the highest in the case of Graves' disease (41.7 microg/g), whereas in the blood samples, the reverse results were found (7.1 microg/g and 4.8 microg/g, respectively). The physical basis of the method used, the experimental setup, and the procedure of sample preparation are described.

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Year:  2001        PMID: 11508625     DOI: 10.1385/BTER:80:3:193

Source DB:  PubMed          Journal:  Biol Trace Elem Res        ISSN: 0163-4984            Impact factor:   3.738


  1 in total

1.  Low pH enhances Sp1 DNA binding activity and interaction with TBP.

Authors:  Takayuki Torigoe; Hiroto Izumi; Yoichiro Yoshida; Hiroshi Ishiguchi; Takashi Okamoto; Hideaki Itoh; Kimitoshi Kohno
Journal:  Nucleic Acids Res       Date:  2003-08-01       Impact factor: 16.971

  1 in total

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