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Literature DB >> 11506279

Applying hormesis in aging research and therapy.

Abstract

Biology of aging is well understood at a descriptive level. Based on these data, biogerontological research is now able to develop various possibilities for intervention. A promising approach for the identification of gerontogenes and gerontogenic processes is through the hormetic effects of mild stress on slowing down aging. Although there are several issues remaining to be resolved, specially with regard to the notion of mild stress, application of hormesis in aging research and therapy is a powerful new approach.

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Year: 2001 PMID： 11506279 DOI： 10.1191/096032701701548034

Source DB: PubMed Journal: Hum Exp Toxicol ISSN： 0960-3271 Impact factor: 2.903

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Cited

10 in total

Applying hormesis in aging research and therapy.

1. Mild heat stress stimulates 20S proteasome and its 11S activator in human fibroblasts undergoing aging in vitro.

2. Anti-ageing strategies: prevention or therapy? Showing ageing from within.

3. Role of hormesis in life extension by caloric restriction.

4. Molecular mechanisms of anti-aging hormetic effects of mild heat stress on human cells.

5. Dietary restriction enhances kainate-induced increase in NCAM while blocking the glial activation in adult rat brain.

6. Tai chi diminishes oxidative stress in Mexican older adults.

7. The unexpected anabolic phenotype and extended longevity of skin fibroblasts after chronic glucocorticoid excess.

8. Hormetic effects of heavy metals in aquatic snails: is a little bit of pollution good?

9. Effect of Tai Chi versus walking on oxidative stress in Mexican older adults.

10. LPS alters pattern of sickness behavior but does not affect glutathione level in aged male rats.