| Literature DB >> 11505970 |
M Feldmann1, R N Maini, J Bondeson, P Taylor, B M Foxwell, F M Brennan.
Abstract
As we enter the 2000's it is clear that cytokine blockade is an effective therapeutic strategy for rheumatoid arthritis. In this brief review, we will review the rationale for anti TNFalpha therapy, the current status of therapy and focus on the regulation of TNFalpha production in rheumatoid synovium. New approaches to studying TNF regulation in RA and of elucidating the controversial role of T cells in this complex disease will be described.Entities:
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Year: 2001 PMID： 11505970 DOI： 10.1007/978-1-4615-1243-1_13
Source DB: PubMed Journal: Adv Exp Med Biol ISSN： 0065-2598 Impact factor: 2.622