| Literature DB >> 11504186 |
Abstract
The dose-dependent effects of chemoattractants on target cell migration such as tumor cells, fibroblasts, and especially neutrophils were assessed. In general, the dose-response characteristics were strikingly biphasic in nature and were independent of both the target tissue and chemoattractant agent. The assessment included evaluations of the quantitative features of the dose-response relationship, mechanistic foundations of the biphasic responsiveness and clinical applications.Entities:
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Year: 2001 PMID： 11504186 DOI： 10.1080/20014091111875
Source DB: PubMed Journal: Crit Rev Toxicol ISSN： 1040-8444 Impact factor: 5.635