Literature DB >> 11503922

Significance of the solid component in predicting malignancy in ovarian cystic teratomas: diagnostic considerations.

A Mlikotic1, L McPhaul, G C Hansen, R M Sinow.   

Abstract

OBJECTIVE: To determine whether gray scale characteristics of the solid components of cystic ovarian teratomas exist that could differentiate more common benign forms from malignant variants.
METHODS: We retrospectively reviewed the sonographic images of 188 ovarian teratomas that contain at least a 25% cystic component and correlated the images with the final diagnosis. Features of the solid component assessed included its echo texture, overall appearance, shape, size, and internal homogeneity.
RESULTS: One-hundred seventy-seven teratomas were benign, and 11 were malignant; among the malignant masses, 7 were high grade. Of the benign forms, 155 solid components (88%) were hyperechoic, 168 (95%) were focal in appearance, 105 (59%) were nodular in shape, and 123 (69%) were uniformly solid. Of the malignant types, 9 solid components (82%) were isoechoic, 6 (55%) had branching, 6 (55%) were irregular in shape, and 8 (73%) were uniformly solid. Five malignant teratomas (45% overall and 71% of high-grade subtypes) had branching isoechoic components. Only 2 benign teratomas (1%) had isoechoic components that branched.
CONCLUSIONS: The presence of a branching isoechoic component in a cystic ovarian teratoma may suggest malignancy.

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Mesh:

Year:  2001        PMID: 11503922     DOI: 10.7863/jum.2001.20.8.859

Source DB:  PubMed          Journal:  J Ultrasound Med        ISSN: 0278-4297            Impact factor:   2.153


  5 in total

Review 1.  Management of asymptomatic ovarian and other adnexal cysts imaged at US: Society of Radiologists in Ultrasound Consensus Conference Statement.

Authors:  Deborah Levine; Douglas L Brown; Rochelle F Andreotti; Beryl Benacerraf; Carol B Benson; Wendy R Brewster; Beverly Coleman; Paul Depriest; Peter M Doubilet; Steven R Goldstein; Ulrike M Hamper; Jonathan L Hecht; Mindy Horrow; Hye-Chun Hur; Mary Marnach; Maitray D Patel; Lawrence D Platt; Elizabeth Puscheck; Rebecca Smith-Bindman
Journal:  Radiology       Date:  2010-05-26       Impact factor: 11.105

2.  Ultrasound features of immature ovarian teratomas: Case series and review of literature.

Authors:  S Abdullahi Idle; K Hayes; J A Ross
Journal:  Ultrasound       Date:  2020-02-11

3.  Risk factors for malignant transformation of mature cystic teratoma.

Authors:  Chan-Hong Park; Min-Hyung Jung; Yong-Il Ji
Journal:  Obstet Gynecol Sci       Date:  2015-11-16

4.  Malignant transformation arising from mature ovarian cystic teratoma: A case series.

Authors:  Li Qin; Tao Zhao; Xin Liu; Hongli Wang; Xin Gu; Dian Chen; Zaiping Wang; Du He
Journal:  Medicine (Baltimore)       Date:  2021-04-02       Impact factor: 1.817

5.  Squamous cell carcinoma arising in a partially ruptured giant mature cystic teratoma: A case report.

Authors:  Jean Sebastein Rowe; Gabriel Makar; Thomas Holdbrook; Pauline Germaine
Journal:  Radiol Case Rep       Date:  2018-10-24
  5 in total

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