Literature DB >> 11502662

The effect of helium on ventilator performance: study of five ventilators and a bedside Pitot tube spirometer.

A Oppenheim-Eden1, Y Cohen, C Weissman, R Pizov.   

Abstract

OBJECTIVE: To assess in vitro the performance of five mechanical ventilators-Siemens 300 and 900C (Siemens-Elma; Solna, Sweden), Puritan Bennett 7200 (Nellcor Puritan Bennett; Pleasanton, CA), Evita 4 (Dragerwerk; Lubeck, Germany), and Bear 1000 (Bear Medical Systems; Riverside CA)-and a bedside sidestream spirometer (Datex CS3 Respiratory Module; Datex-Ohmeda; Helsinki, Finland) during ventilation with helium-oxygen mixtures.
DESIGN: In vitro study.
SETTING: ICUs of two university-affiliated hospitals. METHODS AND MEASUREMENTS: Each ventilator was connected to 100% helium through compressed air inlets and then tested at three to six different tidal volume (VT) settings using various helium-oxygen concentrations (fraction of inspired oxygen [FIO(2)] of 0.2 to 1.0). FIO(2) and VT were measured with the Datex CS3 spirometer, and VT was validated with a water-displacement spirometer. MAIN
RESULTS: The Puritan Bennett 7200 ventilator did not function with helium. With the other four ventilators, delivered FIO(2) was lower than the set FIO(2). For the Siemens 300 and 900C ventilators, this difference could be explained by the lack of 21% oxygen when helium was connected to the air supply port, while for the other two ventilators, a nonlinear relation was found. The VT of the Siemens 300 ventilator was independent of helium concentration, while for the other three ventilators, delivered VT was greater than the set VT and was dependent on helium concentration. During ventilation with 80% helium and 20% oxygen, VT increased to 125% of set VT for the Siemens 900C ventilator, and more than doubled for the Evita 4 and Bear 1000 ventilators. Under the same conditions, the Datex CS3 spirometer underestimated the delivered VT by about 33%.
CONCLUSIONS: At present, no mechanical ventilator is calibrated for use with helium. This investigation offers correction factors for four ventilators for ventilation with helium.

Entities:  

Mesh:

Substances:

Year:  2001        PMID: 11502662     DOI: 10.1378/chest.120.2.582

Source DB:  PubMed          Journal:  Chest        ISSN: 0012-3692            Impact factor:   9.410


  3 in total

1.  Helium-oxygen reduces work of breathing in mechanically ventilated patients with chronic obstructive pulmonary disease.

Authors:  Marc Gainnier; Jean-Michel Arnal; Patrick Gerbeaux; Stéphane Donati; Laurent Papazian; Jean-Marie Sainty
Journal:  Intensive Care Med       Date:  2003-07-25       Impact factor: 17.440

2.  Acute severe asthma: new approaches to assessment and treatment.

Authors:  Spyros A Papiris; Effrosyni D Manali; Likurgos Kolilekas; Christina Triantafillidou; Iraklis Tsangaris
Journal:  Drugs       Date:  2009       Impact factor: 9.546

Review 3.  Clinical review: use of helium-oxygen in critically ill patients.

Authors:  Marc Gainnier; Jean-Marie Forel
Journal:  Crit Care       Date:  2006       Impact factor: 9.097

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.