Literature DB >> 1150237

Probable loose linkage between the ABO locus and Waardenburg syndrome type I.

S Arias, M Mota, A Yánez, M Bolivar.   

Abstract

The possibility of linkage was tested in 3 large kindreds with Waardenburg syndrome type I against the ABO locus. Loose linkage is probably present; the recombination fraction in males, females, and both sexes combined seems to be approximately theta' equals 0.175, theta equals 0.255, and theta', theta equals 0.20, respectively. There are still more informative matings to be studied in those pedigrees, as well as the inminent possibility of determining the phase status in several of them, for the ABO locus and a few other loci.

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Year:  1975        PMID： 1150237     DOI： 10.1007/bf00273330

Source DB:  PubMed          Journal:  Humangenetik        ISSN： 0018-7348


  9 in total

1.  TESTING FOR HETEROGENEITY OF RECOMBINATION FRACTION VALUES IN HUMAN GENETICS.

Authors:  C A SMITH
Journal:  Ann Hum Genet       Date:  1963-11       Impact factor: 1.670

2.  A new syndrome combining developmental anomalies of the eyelids, eyebrows and nose root with pigmentary defects of the iris and head hair and with congenital deafness.

Authors:  P J WAARDENBURG
Journal:  Am J Hum Genet       Date:  1951-09       Impact factor: 11.025

3.  Further linkage scores and corrections in two- and three-generation families.

Authors:  C A Smith
Journal:  Ann Hum Genet       Date:  1969-10       Impact factor: 1.670

4.  Progress in mapping human autosomes.

Authors:  J H Renwick
Journal:  Br Med Bull       Date:  1969-01       Impact factor: 4.291

5.  The Waardenburg syndrome.

Authors:  O A Pantke; M M Cohen
Journal:  Birth Defects Orig Artic Ser       Date:  1971-06

Review 6.  Status and prospects of research in hereditary deafness.

Authors:  W E Nance; F E McConnell
Journal:  Adv Hum Genet       Date:  1973

7.  Analysis for possible linkage between the loci for the Waardenburg syndrome and various blood groups and serological traits.

Authors:  J L Simpson; C T Falk; G Morillo-Cucci; F H Allen; J German
Journal:  Humangenetik       Date:  1974-06-26

8.  Genetic heterogeneity in the Waardenburg syndrome.

Authors:  S Arias
Journal:  Birth Defects Orig Artic Ser       Date:  1971-03

9.  Apparent non-penetrance for dystopia in Waardenburg syndrome type I, with some hints on the diagnosis of dystopia canthorum.

Authors:  S Arias; M Mota
Journal:  J Genet Hum       Date:  1978-06
  9 in total
  3 in total

1.  Mouse and hamster mutants as models for Waardenburg syndromes in humans.

Authors:  J H Asher; T B Friedman
Journal:  J Med Genet       Date:  1990-10       Impact factor: 6.318

2.  Assignment of the AK1:Np:ABO linkage group to human chromosome 9.

Authors:  A Westerveld; A P Jongsma; P Meera Khan; H van Someren; D Bootsma
Journal:  Proc Natl Acad Sci U S A       Date:  1976-03       Impact factor: 11.205

3.  Assignment of the locus for Waardenburg syndrome type I to human chromosome 2q37 and possible homology to the Splotch mouse.

Authors:  C Foy; V Newton; D Wellesley; R Harris; A P Read
Journal:  Am J Hum Genet       Date:  1990-06       Impact factor: 11.025
  3 in total

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