Literature DB >> 11501764

The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development.

G Söhl1, J Eiberger, Y T Jung, C A Kozak, K Willecke.   

Abstract

A novel mouse gap junction gene, coding for a presumptive protein of 258 amino acids (molecular mass: 28 981 Da), has been designated connexin29. This single copy gene was mapped to distal mouse chromosome 5 and shows 75% sequence identity to a human connexin30.2 sequence in the database. Connexin29 mRNA (4.4 kb) is highly expressed in mouse sciatic nerve and less abundant in spinal cord as well as in adult brain, where it increased 12-fold between day 7 and 14 post partum. Our expression data suggest that the new connexin gene is active in myelin-forming glial cells.

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Year:  2001        PMID: 11501764     DOI: 10.1515/BC.2001.122

Source DB:  PubMed          Journal:  Biol Chem        ISSN: 1431-6730            Impact factor:   3.915


  19 in total

Review 1.  Gap junctions in inherited human disorders of the central nervous system.

Authors:  Charles K Abrams; Steven S Scherer
Journal:  Biochim Biophys Acta       Date:  2011-08-16

2.  Connexin29 expression, immunocytochemistry and freeze-fracture replica immunogold labelling (FRIL) in sciatic nerve.

Authors:  Xinbo Li; B D Lynn; C Olson; C Meier; K G V Davidson; T Yasumura; J E Rash; J I Nagy
Journal:  Eur J Neurosci       Date:  2002-09       Impact factor: 3.386

Review 3.  Brain Disorders and Chemical Pollutants: A Gap Junction Link?

Authors:  Marc Mesnil; Norah Defamie; Christian Naus; Denis Sarrouilhe
Journal:  Biomolecules       Date:  2020-12-31

Review 4.  Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue.

Authors:  Jorge E Contreras; Helmuth A Sánchez; Loreto P Véliz; Feliksas F Bukauskas; Michael V L Bennett; Juan C Sáez
Journal:  Brain Res Brain Res Rev       Date:  2004-12

Review 5.  Modulation of brain hemichannels and gap junction channels by pro-inflammatory agents and their possible role in neurodegeneration.

Authors:  Juan A Orellana; Pablo J Sáez; Kenji F Shoji; Kurt A Schalper; Nicolás Palacios-Prado; Victoria Velarde; Christian Giaume; Michael V L Bennett; Juan C Sáez
Journal:  Antioxid Redox Signal       Date:  2009-02       Impact factor: 8.401

6.  Expression of connexin genes in the human retina.

Authors:  Goran Söhl; Antonia Joussen; Norbert Kociok; Klaus Willecke
Journal:  BMC Ophthalmol       Date:  2010-10-27       Impact factor: 2.209

7.  Human oligodendrocytes express Cx31.3: function and interactions with Cx32 mutants.

Authors:  Irene Sargiannidou; Meejin Ahn; Alan D Enriquez; Alejandro Peinado; Richard Reynolds; Charles Abrams; Steven S Scherer; Kleopas A Kleopa
Journal:  Neurobiol Dis       Date:  2008-02-15       Impact factor: 5.996

8.  Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice.

Authors:  Wenxue Tang; Yanping Zhang; Qing Chang; Shoab Ahmad; Ian Dahlke; Hong Yi; Ping Chen; David L Paul; Xi Lin
Journal:  J Neurosci       Date:  2006-02-15       Impact factor: 6.167

9.  A novel mutation in the connexin 29 gene may contribute to nonsyndromic hearing loss.

Authors:  Hui-Mei Hong; Jiann-Jou Yang; Ching-Chyuan Su; Juan-Yu Chang; Tung-Cheng Li; Shuan-Yow Li
Journal:  Hum Genet       Date:  2009-10-30       Impact factor: 4.132

10.  Pathogenesis of X-linked Charcot-Marie-Tooth disease: differential effects of two mutations in connexin 32.

Authors:  Charles K Abrams; Mona Freidin; Feliksas Bukauskas; Kostantin Dobrenis; Thaddeus A Bargiello; Vytas K Verselis; Michael V L Bennett; Lei Chen; Zarife Sahenk
Journal:  J Neurosci       Date:  2003-11-19       Impact factor: 6.167

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