Literature DB >> 11500779

Biological activities of Curcuma longa L.

C C Araújo1, L L Leon.   

Abstract

There are several data in the literature indicating a great variety of pharmacological activities of Curcuma longa L. (Zingiberaceae), which exhibit anti-inflammatory, anti-human immunodeficiency virus, anti-bacteria, antioxidant effects and nematocidal activities. Curcumin is a major component in Curcuma longa L., being responsible for its biological actions. Other extracts of this plant has been showing potency too. In vitro, curcumin exhibits anti-parasitic, antispasmodic, anti-inflammatory and gastrointestinal effects; and also inhibits carcinogenesis and cancer growth. In vivo, there are experiments showing the anti-parasitic, anti-inflammatory potency of curcumin and extracts of C. longa L. by parenteral and oral application in animal models. In this present work we make an overview of the pharmacological activities of C. longa L., showing its importance.

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Year:  2001        PMID: 11500779     DOI: 10.1590/s0074-02762001000500026

Source DB:  PubMed          Journal:  Mem Inst Oswaldo Cruz        ISSN: 0074-0276            Impact factor:   2.743


  107 in total

Review 1.  Colorectal cancer: chemopreventive role of curcumin and resveratrol.

Authors:  Vaishali B Patel; Sabeena Misra; Bhaumik B Patel; Adhip P N Majumdar
Journal:  Nutr Cancer       Date:  2010       Impact factor: 2.900

2.  Epigenetic changes induced by curcumin and other natural compounds.

Authors:  Simone Reuter; Subash C Gupta; Byoungduck Park; Ajay Goel; Bharat B Aggarwal
Journal:  Genes Nutr       Date:  2011-04-24       Impact factor: 5.523

3.  Curcumin suppresses T cell activation by blocking Ca2+ mobilization and nuclear factor of activated T cells (NFAT) activation.

Authors:  Christian Kliem; Anette Merling; Marco Giaisi; Rebecca Köhler; Peter H Krammer; Min Li-Weber
Journal:  J Biol Chem       Date:  2012-02-02       Impact factor: 5.157

4.  Protective effect of curcumin and its combination with piperine (bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence.

Authors:  Mahendra Bishnoi; Kanwaljit Chopra; Lu Rongzhu; Shrinivas K Kulkarni
Journal:  Neurotox Res       Date:  2010-11-13       Impact factor: 3.911

5.  The antibacterial activity of traditionally used Salvadora persica L. (miswak) and Commiphora gileadensis (palsam) in Saudi Arabia.

Authors:  Abdulbasit I I Al-sieni
Journal:  Afr J Tradit Complement Altern Med       Date:  2013-11-02

6.  Protective in vivo effect of curcumin on copper genotoxicity evaluated by comet and micronucleus assays.

Authors:  Alfredo Corona-Rivera; Patricia Urbina-Cano; Lucina Bobadilla-Morales; José de Jesus Vargas-Lares; Mario Alberto Ramirez-Herrera; Maria Luisa Mendoza-Magaua; Rogelio Troyo-Sanroman; Pedro Diaz-Esquivel; Jorge Roman Corona-Rivera
Journal:  J Appl Genet       Date:  2007       Impact factor: 3.240

7.  Interaction of curcumin and diacetylcurcumin with the lipocalin member beta-lactoglobulin.

Authors:  Fakhrossadat Mohammadi; Abdol-Khalegh Bordbar; Adeleh Divsalar; Khosro Mohammadi; Ali Akbar Saboury
Journal:  Protein J       Date:  2009-05       Impact factor: 2.371

8.  Hypocholesterolemic effects of curcumin via up-regulation of cholesterol 7a-hydroxylase in rats fed a high fat diet.

Authors:  Minji Kim; Yangha Kim
Journal:  Nutr Res Pract       Date:  2010-06-28       Impact factor: 1.926

9.  Analysis of binding interaction of curcumin and diacetylcurcumin with human and bovine serum albumin using fluorescence and circular dichroism spectroscopy.

Authors:  Fakhrossadat Mohammadi; Abdol-Khalegh Bordbar; Adeleh Divsalar; Khosro Mohammadi; Ali Akbar Saboury
Journal:  Protein J       Date:  2009-05       Impact factor: 2.371

10.  A Pilot Cross-Over Study to Evaluate Human Oral Bioavailability of BCM-95CG (Biocurcumax), A Novel Bioenhanced Preparation of Curcumin.

Authors:  B Antony; B Merina; V S Iyer; N Judy; K Lennertz; S Joyal
Journal:  Indian J Pharm Sci       Date:  2008 Jul-Aug       Impact factor: 0.975

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