OBJECTIVES: The purpose of this study was to validate cardiac measurements derived from real-time cardiac magnetic resonance imaging (MRI) as compared with well-validated conventional cine MRI. BACKGROUND: Although cardiac MRI provides accurate assessment of left ventricular (LV) volume and mass, most techniques have been relatively slow and required electrocardiogram (ECG) gating over many heart beats. A newly developed real-time MRI system allows continuous real-time dynamic acquisition and display without cardiac gating or breath-holding. METHODS: Fourteen healthy volunteers and nine patients with heart failure underwent real-time and cine MRI in the standard short-axis orientation with a 1.5T MRI scanner. Nonbreath-holding cine MRI was performed with ECG gating and respiratory compensation. Left ventricular end-diastolic volume (LVEDV), left ventricular endsystolic volume (LVESV), ejection fraction (EF) and LV mass calculated from the images obtained by real-time MRI were compared to those obtained by cine MRI. RESULTS: The total study time including localization for real-time MRI was significantly shorter than cine MRI (8.6 +/- 2.3 vs. 24.7 +/- 3.5 min, p < 0.001). Both imaging techniques yielded good quality images allowing cardiac measurements. The measurements of LVEDV, LVESV, EF and LV mass obtained with real-time MRI showed close correlation with those obtained with cine MRI (LVEDV: r = 0.985, p < 0.001; LVESV: r = 0.994, p < 0.001; EF: r = 0.975, p < 0.001; LV mass: r = 0.977, p < 0.001). CONCLUSIONS: Real-time MRI provides accurate measurements of LV volume and mass in a time-efficient manner with respect to image acquisition.
OBJECTIVES: The purpose of this study was to validate cardiac measurements derived from real-time cardiac magnetic resonance imaging (MRI) as compared with well-validated conventional cine MRI. BACKGROUND: Although cardiac MRI provides accurate assessment of left ventricular (LV) volume and mass, most techniques have been relatively slow and required electrocardiogram (ECG) gating over many heart beats. A newly developed real-time MRI system allows continuous real-time dynamic acquisition and display without cardiac gating or breath-holding. METHODS: Fourteen healthy volunteers and nine patients with heart failure underwent real-time and cine MRI in the standard short-axis orientation with a 1.5T MRI scanner. Nonbreath-holding cine MRI was performed with ECG gating and respiratory compensation. Left ventricular end-diastolic volume (LVEDV), left ventricular endsystolic volume (LVESV), ejection fraction (EF) and LV mass calculated from the images obtained by real-time MRI were compared to those obtained by cine MRI. RESULTS: The total study time including localization for real-time MRI was significantly shorter than cine MRI (8.6 +/- 2.3 vs. 24.7 +/- 3.5 min, p < 0.001). Both imaging techniques yielded good quality images allowing cardiac measurements. The measurements of LVEDV, LVESV, EF and LV mass obtained with real-time MRI showed close correlation with those obtained with cine MRI (LVEDV: r = 0.985, p < 0.001; LVESV: r = 0.994, p < 0.001; EF: r = 0.975, p < 0.001; LV mass: r = 0.977, p < 0.001). CONCLUSIONS: Real-time MRI provides accurate measurements of LV volume and mass in a time-efficient manner with respect to image acquisition.
Authors: S Matthew; S J Gandy; R S Nicholas; S A Waugh; E A Crowe; R A Lerski; M H Dunn; J G Houston Journal: Br J Radiol Date: 2012-07 Impact factor: 3.039
Authors: A Bailly; J Lipiecki; P Chabrot; A Alfidja; J M Garcier; S Ughetto; J Ponsonnaille; L Boyer Journal: Surg Radiol Anat Date: 2008-10-08 Impact factor: 1.246
Authors: Bradley D Allen; Maria Carr; Marcos P F Botelho; Amir Ali Rahsepar; Michael Markl; Michael O Zenge; Michaela Schmidt; Mariappan S Nadar; Bruce Spottiswoode; Jeremy D Collins; James C Carr Journal: Int J Cardiovasc Imaging Date: 2016-02-19 Impact factor: 2.357
Authors: Adam Rich; Michael Gregg; Ning Jin; Yingmin Liu; Lee Potter; Orlando Simonetti; Rizwan Ahmad Journal: Magn Reson Med Date: 2019-11-12 Impact factor: 4.668
Authors: Li Feng; Monvadi B Srichai; Ruth P Lim; Alexis Harrison; Wilson King; Ganesh Adluru; Edward V R Dibella; Daniel K Sodickson; Ricardo Otazo; Daniel Kim Journal: Magn Reson Med Date: 2012-08-06 Impact factor: 4.668
Authors: Peter Kellman; Christophe Chefd'hotel; Christine H Lorenz; Christine Mancini; Andrew E Arai; Elliot R McVeigh Journal: Magn Reson Med Date: 2009-12 Impact factor: 4.668