Literature DB >> 11498356

Regulation of pleiotropic drug resistance in yeast.

Anna Kolaczkowska1, Andre Goffeau.   

Abstract

This review focuses on the molecular mechanisms involved in the regulation of multiple drug resistance in the model yeast Saccharomyces cerevisiae and the pathogenic fungus Candida albicans. Recent developments in the study of the transcription factors Pdr1p, Pdr3p and Yap1p are reported. Understanding the molecular basis leading to multiple drug resistance is a prerequisite for the development of new antifungal therapeutics. Copyright 1999 Harcourt Publishers Ltd.

Entities:  

Year:  1999        PMID： 11498356     DOI： 10.1054/drup.1999.0113

Source DB:  PubMed          Journal:  Drug Resist Updat        ISSN： 1368-7646            Impact factor:   18.500


  23 in total

1.  New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system.

Authors:  Stéphane Le Crom; Frédéric Devaux; Philippe Marc; Xiaoting Zhang; W Scott Moye-Rowley; Claude Jacq
Journal:  Mol Cell Biol       Date:  2002-04       Impact factor: 4.272

2.  Phenotypic analysis of genes encoding yeast zinc cluster proteins.

Authors:  B Akache; K Wu; B Turcotte
Journal:  Nucleic Acids Res       Date:  2001-05-15       Impact factor: 16.971

3.  Population genomics of drug resistance in Candida albicans.

Authors:  Leah E Cowen; André Nantel; Malcolm S Whiteway; David Y Thomas; Daniel C Tessier; Linda M Kohn; James B Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  2002-06-27       Impact factor: 11.205

4.  Mode of selection and experimental evolution of antifungal drug resistance in Saccharomyces cerevisiae.

Authors:  James B Anderson; Caroline Sirjusingh; Ainslie B Parsons; Charles Boone; Claire Wickens; Leah E Cowen; Linda M Kohn
Journal:  Genetics       Date:  2003-04       Impact factor: 4.562

5.  Isolation, heterological cloning and sequencing of the RPL28 gene in Kluyveromyces lactis.

Authors:  Maria Takacova; Peter Sklenar; Yvetta Gbelska; Karin Breunig; Julius Subik
Journal:  Curr Genet       Date:  2002-09-27       Impact factor: 3.886

Review 6.  A fungal family of transcriptional regulators: the zinc cluster proteins.

Authors:  Sarah MacPherson; Marc Larochelle; Bernard Turcotte
Journal:  Microbiol Mol Biol Rev       Date:  2006-09       Impact factor: 11.056

7.  KNQ1, a Kluyveromyces lactis gene encoding a drug efflux permease.

Authors:  Maria Takacova; Denisa Imrichova; Jana Cernicka; Yvetta Gbelska; Julius Subik
Journal:  Curr Genet       Date:  2003-11-01       Impact factor: 3.886

8.  Promoter-dependent disruption of genes: simple, rapid, and specific PCR-based method with application to three different yeast.

Authors:  Thomas D Edlind; Karl W Henry; John-Paul Vermitsky; Merritt P Edlind; Shriya Raj; Santosh K Katiyar
Journal:  Curr Genet       Date:  2005-09-14       Impact factor: 3.886

9.  Azole resistance in Candida glabrata: coordinate upregulation of multidrug transporters and evidence for a Pdr1-like transcription factor.

Authors:  John-Paul Vermitsky; Thomas D Edlind
Journal:  Antimicrob Agents Chemother       Date:  2004-10       Impact factor: 5.191

10.  Pdr3 is required for DNA damage induction of MAG1 and DDI1 via a bi-directional promoter element.

Authors:  Yu Zhu; Wei Xiao
Journal:  Nucleic Acids Res       Date:  2004-09-27       Impact factor: 16.971
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