Literature DB >> 1149818

Apomorphine as a discriminative stimulus, and its antagonism by haloperidol.

F C Colpaert, C J Niemegeers, J J Kuyps, P A Janssen.   

Abstract

At a non-stereotypogenic dose (0.16 mg/kg, s.c.), apomorphine was shown to produce a discriminative stimulus in rats. The apomorphine-produced stimulus was found to be effectively antagonized by haloperidol. It is suggested that apomorphine's ability to stimulate central dopamine receptors is directly related to its cueing action.

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Year:  1975        PMID: 1149818     DOI: 10.1016/0014-2999(75)90310-6

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


  9 in total

1.  Theoretical and methodological considerations on drug discrimination learning.

Authors:  F C Colpaert; C J Niemegeers; P A Janssen
Journal:  Psychopharmacologia       Date:  1976-03-16

2.  Drug Discrimination and the Analysis of Private Events.

Authors:  Brian D Kangas; David R Maguire
Journal:  Behav Anal (Wash D C)       Date:  2016-03-14

3.  Discriminative stimulus properties of fenfluramine in an operant task: an analysis of its cue function.

Authors:  A J Goudie
Journal:  Psychopharmacology (Berl)       Date:  1977-06-06       Impact factor: 4.530

4.  The rise (and fall?) of drug discrimination research.

Authors:  Lance R McMahon
Journal:  Drug Alcohol Depend       Date:  2015-06-01       Impact factor: 4.492

5.  Discriminative stimulus effects of a low dose of apomorphine in the rat.

Authors:  A H Tang; S R Franklin
Journal:  Psychopharmacology (Berl)       Date:  1987       Impact factor: 4.530

6.  The discriminative stimulus properties of buspirone involve dopamine-2 receptor antagonist activity.

Authors:  H J Rijnders; J L Slangen
Journal:  Psychopharmacology (Berl)       Date:  1993       Impact factor: 4.530

7.  Differential effects of apomorphine in 6-hydroxydopamine-treated and aged rats.

Authors:  M D Schechter; J T Concannon
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

8.  Response changes after repeated low apomorphine: dopamine autoreceptor desensitization or learning?

Authors:  V J Nickolson; H van Riezen; A M van Delft
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

9.  Ability of 3-carboxysalsolinol to produce ethanol-like discrimination in rats.

Authors:  M D Schechter
Journal:  Psychopharmacology (Berl)       Date:  1980       Impact factor: 4.530

  9 in total

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