| Literature DB >> 11495803 |
A Scherf1, L M Figueiredo, L H Freitas-Junior.
Abstract
New data on the organization of plasmodial telomeres has recently become available. Telomeres form clusters of four to seven heterologous chromosome ends at the nuclear periphery in asexual and sexual parasite stages. This subnuclear compartment promotes gene conversion between members of subtelomeric virulence factor genes in heterologous chromosomes resulting in diversity of antigenic and adhesive phenotypes. This has important implications for parasite survival.Mesh:
Year: 2001 PMID: 11495803 DOI: 10.1016/s1369-5274(00)00227-7
Source DB: PubMed Journal: Curr Opin Microbiol ISSN: 1369-5274 Impact factor: 7.934