Literature DB >> 11495738

The design of antiparallel coiled coils.

M G Oakley1, J J Hollenbeck.   

Abstract

Recent structural studies have highlighted the importance of antiparallel coiled coils in nature. In addition, well-behaved, model antiparallel coiled coils have been designed and used for the reassembly of protein fragments and for the study of the energetic contributions of various interactions to helix orientation specificity. Finally, high-resolution structural data are available for designed helical bundles, allowing an evaluation of the success of state-of-the-art protein design efforts.

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Year:  2001        PMID： 11495738     DOI： 10.1016/s0959-440x(00)00232-3

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN： 0959-440X            Impact factor:   6.809


  51 in total

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