Literature DB >> 11494869

Exploiting anthracycline scaffold for designing DNA-targeting agents.

W Priebe1, I Fokt, T Przewloka, J B Chaires, J Portugal, J O Trent.   

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Year:  2001        PMID： 11494869     DOI： 10.1016/s0076-6879(01)40441-1

Source DB:  PubMed          Journal:  Methods Enzymol        ISSN： 0076-6879            Impact factor:   1.600


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  13 in total

1.  Thermodynamic characterization of the multivalent binding of chartreusin to DNA.

Authors:  Francisca Barceló; Damiana Capó; José Portugal
Journal:  Nucleic Acids Res       Date:  2002-10-15       Impact factor: 16.971

2.  Design, synthesis and biological evaluation of a novel series of anthrapyrazoles linked with netropsin-like oligopyrrole carboxamides as anticancer agents.

Authors:  Rui Zhang; Xing Wu; Lynn J Guziec; Frank S Guziec; Gaik-Lean Chee; Jack C Yalowich; Brian B Hasinoff
Journal:  Bioorg Med Chem       Date:  2010-04-18       Impact factor: 3.641

3.  A new bisintercalating anthracycline with picomolar DNA binding affinity.

Authors:  José Portugal; Derek J Cashman; John O Trent; Neus Ferrer-Miralles; Teresa Przewloka; Izabela Fokt; Waldemar Priebe; Jonathan B Chaires
Journal:  J Med Chem       Date:  2005-12-29       Impact factor: 7.446

4.  Design, synthesis, and biological evaluation of a novel series of bisintercalating DNA-binding piperazine-linked bisanthrapyrazole compounds as anticancer agents.

Authors:  Rui Zhang; Xing Wu; Jack C Yalowich; Brian B Hasinoff
Journal:  Bioorg Med Chem       Date:  2011-10-14       Impact factor: 3.641

5.  Promoter-specific inhibition of transcription by daunorubicin in Saccharomyces cerevisiae.

Authors:  Silvia Marín; Sylvia Mansilla; Natàlia García-Reyero; Marta Rojas; José Portugal; Benjamin Piña
Journal:  Biochem J       Date:  2002-11-15       Impact factor: 3.857

6.  Evaluation of molecular descriptors for antitumor drugs with respect to noncovalent binding to DNA and antiproliferative activity.

Authors:  José Portugal
Journal:  BMC Pharmacol       Date:  2009-09-16

7.  Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform.

Authors:  Brian B Hasinoff; Xing Wu; Daywin Patel; Ragu Kanagasabai; Soumendrakrishna Karmahapatra; Jack C Yalowich
Journal:  J Pharmacol Exp Ther       Date:  2015-12-11       Impact factor: 4.030

8.  The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds.

Authors:  Brian B Hasinoff; Hong Liang; Xing Wu; Lynn J Guziec; Frank S Guziec; Kyle Marshall; Jack C Yalowich
Journal:  Bioorg Med Chem       Date:  2008-01-26       Impact factor: 3.641

9.  Inhibition of N-terminal lysines acetylation and transcription factor assembly by epirubicin induced deranged cell homeostasis.

Authors:  Shahper N Khan; Mohd Danishuddin; Bhavna Varshney; Sunil K Lal; Asad U Khan
Journal:  PLoS One       Date:  2012-12-14       Impact factor: 3.240

10.  Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells.

Authors:  KangAe Lee; David Z Qian; Sergio Rey; Hong Wei; Jun O Liu; Gregg L Semenza
Journal:  Proc Natl Acad Sci U S A       Date:  2009-01-23       Impact factor: 12.779
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