| Literature DB >> 11493246 |
A M Ho1, P Dion, M K Karmakar, G Cheng, J L Derrick, D C Chung, B A Tay.
Abstract
A theoretical one-compartment pharmacokinetic model is described, the aim of which is to guide factor VIII replacement therapy in patients with haemophilia A suffering from significant and ongoing haemorrhage. Based on our calculations, plasma factor VIII concentrations can decrease at a rapid rate even with non-severe blood loss.Entities:
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Year: 2001 PMID： 11493246 DOI： 10.1046/j.1365-2044.2001.02058-3.x
Source DB: PubMed Journal: Anaesthesia ISSN： 0003-2409 Impact factor: 6.955