OBJECTIVE: To investigate the effects of the home environment, socioeconomic status (SES), and health status on cognitive functioning in a sample of children with HIV-1 infection in a cross-sectional study. METHODS: Forty-three caregivers and their children (2.5 to 12 years) participated. Caregivers completed two self-report measures of the home environment that included questions regarding the organization of the environment, play materials, parental involvement, variety of stimulation, and parental attitudes toward the provision of a cognitively stimulating environment. Cognitive functioning was assessed using a standardized intelligence (IQ) test. Children's medical charts were reviewed for HIV-1 classification status (CDC, 1994), CD4 cell counts, and current medication. RESULTS: This study revealed two primary findings. First, measures of the home environment mediated the association between SES and child IQ. Second, measures of the home environment had a stronger association with child IQ during the advanced stages of disease than earlier stages of disease. CONCLUSIONS: The home environment is associated with cognitive functioning among children with HIV-1 infection. Moreover, interventions aimed at enhancing the quality of the home environment may have a positive impact on these children's cognitive development.
OBJECTIVE: To investigate the effects of the home environment, socioeconomic status (SES), and health status on cognitive functioning in a sample of children with HIV-1 infection in a cross-sectional study. METHODS: Forty-three caregivers and their children (2.5 to 12 years) participated. Caregivers completed two self-report measures of the home environment that included questions regarding the organization of the environment, play materials, parental involvement, variety of stimulation, and parental attitudes toward the provision of a cognitively stimulating environment. Cognitive functioning was assessed using a standardized intelligence (IQ) test. Children's medical charts were reviewed for HIV-1 classification status (CDC, 1994), CD4 cell counts, and current medication. RESULTS: This study revealed two primary findings. First, measures of the home environment mediated the association between SES and child IQ. Second, measures of the home environment had a stronger association with child IQ during the advanced stages of disease than earlier stages of disease. CONCLUSIONS: The home environment is associated with cognitive functioning among children with HIV-1 infection. Moreover, interventions aimed at enhancing the quality of the home environment may have a positive impact on these children's cognitive development.
Authors: Katrina D Hermetet-Lindsay; Katharine F Correia; Paige L Williams; Renee Smith; Kathleen M Malee; Claude A Mellins; Richard M Rutstein Journal: AIDS Behav Date: 2017-09
Authors: Luminita Ene; Donald R Franklin; Ruxandra Burlacu; Anca E Luca; Andreea G Blaglosov; Ronald J Ellis; Terry J Alexander; Anya Umlauf; Igor Grant; Dan C Duiculescu; Cristian L Achim; Thomas D Marcotte Journal: J Neurovirol Date: 2014-09-04 Impact factor: 2.643
Authors: Elizabeth Brackis-Cott; Ezer Kang; Curtis Dolezal; Elaine J Abrams; Claude Ann Mellins Journal: J Pediatr Health Care Date: 2008-04-08 Impact factor: 1.812
Authors: Thomas M Burbacher; Kimberly S Grant; Julie Worlein; James Ha; Eliza Curnow; Sandra Juul; Gene P Sackett Journal: Am J Primatol Date: 2013-07-19 Impact factor: 2.371
Authors: Hallam Hurt; Laura M Betancourt; Elsa K Malmud; David M Shera; Joan M Giannetta; Nancy L Brodsky; Martha J Farah Journal: Neurotoxicol Teratol Date: 2009-08-15 Impact factor: 3.763
Authors: Esau G Mbewe; Pelekelo P Kabundula; Sylvia Mwanza-Kabaghe; Alexandra Buda; Heather R Adams; Colleen Schneider; Michael J Potchen; Milimo Mweemba; Manoj Mathews; J Anitha Menon; Bo Wang; Travis Baseler; Alex Paciorkowski; Gretchen L Birbeck; David R Bearden Journal: J Acquir Immune Defic Syndr Date: 2022-01-01 Impact factor: 3.771