Literature DB >> 11489510

Potential of block copolymer- and immuno-conjugates for tumor-targeted delivery of Bowman-Birk soybean proteinase inhibitor.

I P Gladysheva1, O V Polekhina, T A Karmakova, E R Nemtsova, R I Yakubovskaya, W C Shen, A R Kennedy, N I Larionova.   

Abstract

The present work reports the effect of conjugation of the anticarcinogenic and antitumor soybean Bowman-Birk protease inhibitor (BBI) with amphiphilic block copolymer of ethylene oxide and propylene oxide (PEO-PPO) as well as with monoclonal antibody via clinical dextran (D) on tumor-targeted delivery of BBI.

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Year:  2001        PMID: 11489510     DOI: 10.1016/s0168-3659(01)00337-6

Source DB:  PubMed          Journal:  J Control Release        ISSN: 0168-3659            Impact factor:   9.776


  1 in total

1.  Construction of humanized carcinoembryonic antigen specific single chain variable fragment and mitomycin conjugate.

Authors:  De-Jie Chen; Zui Tan; Feng Chen; Tian Du
Journal:  World J Gastroenterol       Date:  2007-11-21       Impact factor: 5.742

  1 in total

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