Literature DB >> 11486795

A gene required for the specification of dorsal-ventral pattern in Drosophila appears to encode a serine protease.

R DeLotto1, P Spierer.   

Abstract

The maternal effect gene snake is required for the establishment of the dorsal-ventral axis during the embryonic development of Drosophila. The molecular cloning of the gene and analysis of a complementary DNA sequence suggest that the gene encodes a serine protease which is structurally similar to proteases involved in blood clotting, peptide processing, and complement fixation pathways.

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Year:  1986        PMID: 11486795     DOI: 10.1038/323688a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  33 in total

1.  Interallelic complementation at the Drosophila melanogaster gastrulation defective locus defines discrete functional domains of the protein.

Authors:  G Ponomareff; H Giordano; Y DeLotto; R DeLotto
Journal:  Genetics       Date:  2001-10       Impact factor: 4.562

2.  Autoproteolysis and feedback in a protease cascade directing Drosophila dorsal-ventral cell fate.

Authors:  M Dissing; H Giordano; R DeLotto
Journal:  EMBO J       Date:  2001-05-15       Impact factor: 11.598

3.  Endocytosis is required for Toll signaling and shaping of the Dorsal/NF-kappaB morphogen gradient during Drosophila embryogenesis.

Authors:  Viktor K Lund; Yvonne DeLotto; Robert DeLotto
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-04       Impact factor: 11.205

4.  The l(3)S12 locus of Drosophila melanogaster: heterochromatic position effects and stage-specific misexpression of the gene in P element transposons.

Authors:  F L Dutton; A Chovnick
Journal:  Genetics       Date:  1991-05       Impact factor: 4.562

5.  Genetic and molecular characterization of tube, a Drosophila gene maternally required for embryonic dorsoventral polarity.

Authors:  A Letsou; S Alexander; K Orth; S A Wasserman
Journal:  Proc Natl Acad Sci U S A       Date:  1991-02-01       Impact factor: 11.205

6.  A common domain within the proenzyme regions of the Drosophila snake and easter proteins and Tachypleus proclotting enzyme defines a new subfamily of serine proteases.

Authors:  C L Smith; R DeLotto
Journal:  Protein Sci       Date:  1992-09       Impact factor: 6.725

7.  Distinct functional specificities are associated with protein isoforms encoded by the Drosophila dorsal-ventral patterning gene pipe.

Authors:  Zhenyu Zhang; Xianjun Zhu; Leslie M Stevens; David Stein
Journal:  Development       Date:  2009-08       Impact factor: 6.868

8.  Mutagenesis of the cysteine-rich clip domain in the Drosophila patterning protease, Snake.

Authors:  Sufang Tian; Ellen K LeMosy
Journal:  Arch Biochem Biophys       Date:  2008-05-01       Impact factor: 4.013

9.  The rosy region of Drosophila melanogaster and Drosophila simulans. I. Contrasting levels of naturally occurring DNA restriction map variation and divergence.

Authors:  C F Aquadro; K M Lado; W A Noon
Journal:  Genetics       Date:  1988-08       Impact factor: 4.562

10.  The Drosophila Stubble-stubbloid gene encodes an apparent transmembrane serine protease required for epithelial morphogenesis.

Authors:  L F Appel; M Prout; R Abu-Shumays; A Hammonds; J C Garbe; D Fristrom; J Fristrom
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-01       Impact factor: 11.205

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