H M Yang1. 1. Departamento de Matemática Aplicada, Instituto de Matemática, Estatística e Computação Científica, Universidade Estadual de Campinas, Campinas, SP, Brasil. hyunyang@ime.unicamp.br
Abstract
OBJECTIVE: Sensitivity analysis was applied to a mathematical model describing malaria transmission relating global warming and local socioeconomic conditions. METHODS: A previous compartment model was proposed to describe the overall transmission of malaria. This model was built up on several parameters and the prevalence of malaria in a community was characterized by the values assigned to them. To assess the control efforts, the model parameters can vary on broad intervals. RESULTS: By performing the sensitivity analysis on equilibrium points, which represent the level of malaria infection in a community, the different possible scenarios are obtained when the parameters are changed. CONCLUSIONS: Depending on malaria risk, the efforts to control its transmission can be guided by a subset of parameters used in the mathematical model.
OBJECTIVE: Sensitivity analysis was applied to a mathematical model describing malaria transmission relating global warming and local socioeconomic conditions. METHODS: A previous compartment model was proposed to describe the overall transmission of malaria. This model was built up on several parameters and the prevalence of malaria in a community was characterized by the values assigned to them. To assess the control efforts, the model parameters can vary on broad intervals. RESULTS: By performing the sensitivity analysis on equilibrium points, which represent the level of malaria infection in a community, the different possible scenarios are obtained when the parameters are changed. CONCLUSIONS: Depending on malaria risk, the efforts to control its transmission can be guided by a subset of parameters used in the mathematical model.
Authors: Paul E Parham; Joanna Waldock; George K Christophides; Deborah Hemming; Folashade Agusto; Katherine J Evans; Nina Fefferman; Holly Gaff; Abba Gumel; Shannon LaDeau; Suzanne Lenhart; Ronald E Mickens; Elena N Naumova; Richard S Ostfeld; Paul D Ready; Matthew B Thomas; Jorge Velasco-Hernandez; Edwin Michael Journal: Philos Trans R Soc Lond B Biol Sci Date: 2015-04-05 Impact factor: 6.237