Literature DB >> 11485491

One-carbon homologation of carboxylic acids via BtCH(2)TMS: a safe alternative to the Arndt--Eistert reaction.

A R Katritzky1, S Zhang, A H Hussein, Y Fang, P J Steel.   

Abstract

Carboxylic acids are converted into the corresponding homologated acids or esters, using easily available 1-(trimethylsilylmethyl)benzotriazole (1) as a one-carbon synthon. The effectiveness of the reaction has been investigated on six aryl and seven alkyl carboxylic acids.

Entities:  

Year:  2001        PMID: 11485491     DOI: 10.1021/jo0017640

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  1 in total

Review 1.  Preparation and Utility of N-Alkynyl Azoles in Synthesis.

Authors:  Brandon Reinus; Sean M Kerwin
Journal:  Molecules       Date:  2019-01-24       Impact factor: 4.411

  1 in total

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