Literature DB >> 11485488

Syntheses of 1,4-benzothiazepines and 1,4-benzoxazepines via cyclizations of 1-[2-arylthio(oxy)ethyl]-5-benzotriazolyl-2-pyrrolidinones and 3-benzotriazolyl-2-[2-arylthio(oxy)ethyl]-1-isoindolinones.

A R Katritzky1, Y J Xu, H Y He, S Mehta.   

Abstract

1-[2-Arylthio(oxy)ethyl]-5-benzotriazolyl-2-pyrrolidinones 6a-e, 12 and 3-benzotriazolyl-2-[2-arylthio(oxy)ethyl]-1-isoindolinones 9a-f, 14 are readily available from reactions of benzotriazole (4), 2-(arylsulfanyl)ethylamines 3, or 2-phenoxyethylamine (11) with 2,5-dimethoxy-2,5-dihydrofuran (5) or 2-formylbenzoic acid (8). Lewis acid mediated cyclizations of 6 and 9 produced novel 1,4-benzothiazepines 7a-e and 10a-f, respectively. Cyclizations of 12 and 14 gave 1,4-benzoxazepines 13 and 15, respectively.

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Year:  2001        PMID： 11485488     DOI： 10.1021/jo010179b

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  2 in total

1.  Tuning of the copper-thioether bond in tetradentate N₃S(thioether) ligands; O-O bond reductive cleavage via a [Cu(II)₂(μ-1,2-peroxo)]²⁺/[Cu(III)₂(μ-oxo)₂]²⁺ equilibrium.

Authors:  Sunghee Kim; Jake W Ginsbach; A Imtiaz Billah; Maxime A Siegler; Cathy D Moore; Edward I Solomon; Kenneth D Karlin
Journal:  J Am Chem Soc       Date:  2014-05-22       Impact factor: 15.419

2.  Ultra-small palladium nano-particles synthesized using bulky S/Se and N donor ligands as a stabilizer: application as catalysts for Suzuki-Miyaura coupling.

Authors:  Preeti Oswal; Aayushi Arora; Jolly Kaushal; Gyandshwar Kumar Rao; Sushil Kumar; Ajai K Singh; Arun Kumar
Journal:  RSC Adv       Date:  2019-07-18       Impact factor: 4.036
  2 in total

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