| Literature DB >> 11485459 |
E M Santangelo1, D Rotticci, I Liblikas, T Norin, C R Unelius.
Abstract
A short synthetic route to asymmetric iridoids was developed. The three key steps were an intramolecular [4 + 2] cycloaddition reaction of an enamine derivative of 8-oxocitral (2), a dynamic acetylation, and an enzymatic resolution of the gastrolactyl acetates 5a and 5b, iridoids with three stereocenters. Some regio- and stereoselective heterogeneous catalytic hydrogenations of double bonds in iridoid aglucones were discussed.Entities:
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Year: 2001 PMID： 11485459 DOI： 10.1021/jo015592y
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354