Literature DB >> 11485206

Type I interferons and herpes simplex virus infection: a naked DNA approach as a therapeutic option?

S Noisakran1, D J Carr.   

Abstract

Herpes simplex virus (HSV) types 1 and 2 are highly successful human pathogens that can elicit blinding herpetic keratoconjunctivitis, fatal sporadic encephalitis, aseptic meningitis, and increase the risk of acquiring additional sexually transmitted diseases. Type I interferons (IFN) play a significant role in controlling HSV pathogenesis by antagonizing viral replication and spread. Taking advantage of the susceptibility of HSV to IFNs, a novel approach of employing plasmid DNA cassettes expressing type 1 IFNs to antagonize viral pathogenesis has been undertaken. This review will describe recent work in our lab and those of others using naked DNA encoding cytokines to antagonize HSV replication and virus trafficking or immune-mediated pathogenesis as a result of viral assault to ocular tissue.

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Year:  2001        PMID： 11485206     DOI： 10.1385/IR:24:1:01

Source DB:  PubMed          Journal:  Immunol Res        ISSN： 0257-277X            Impact factor:   2.829


  55 in total

1.  Lymphocytes delay kinetics of HSV-1 reactivation from in vitro explants of latent infected trigeminal ganglia.

Authors:  S Noisakran; D J Carr
Journal:  J Neuroimmunol       Date:  1999-03-01       Impact factor: 3.478

2.  Absence of macrophage inflammatory protein-1alpha prevents the development of blinding herpes stromal keratitis.

Authors:  T M Tumpey; H Cheng; D N Cook; O Smithies; J E Oakes; R N Lausch
Journal:  J Virol       Date:  1998-05       Impact factor: 5.103

3.  Suppression of ongoing ocular inflammatory disease by topical administration of plasmid DNA encoding IL-10.

Authors:  M Daheshia; N Kuklin; S Kanangat; E Manickan; B T Rouse
Journal:  J Immunol       Date:  1997-08-15       Impact factor: 5.422

4.  On the essential involvement of neutrophils in the immunopathologic disease: herpetic stromal keratitis.

Authors:  J Thomas; S Gangappa; S Kanangat; B T Rouse
Journal:  J Immunol       Date:  1997-02-01       Impact factor: 5.422

Review 5.  Transcription of the herpes simplex virus genome during productive and latent infection.

Authors:  E K Wagner; J F Guzowski; J Singh
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1995

6.  Herpes simplex virus type 1 renders infected cells resistant to cytotoxic T-lymphocyte-induced apoptosis.

Authors:  K R Jerome; J F Tait; D M Koelle; L Corey
Journal:  J Virol       Date:  1998-01       Impact factor: 5.103

7.  Role of MIP-2 in neutrophil migration and tissue injury in the herpes simplex virus-1-infected cornea.

Authors:  X T Yan; T M Tumpey; S L Kunkel; J E Oakes; R N Lausch
Journal:  Invest Ophthalmol Vis Sci       Date:  1998-09       Impact factor: 4.799

Review 8.  Role of early cytokines, including alpha and beta interferons (IFN-alpha/beta), in innate and adaptive immune responses to viral infections.

Authors:  C A Biron
Journal:  Semin Immunol       Date:  1998-10       Impact factor: 11.130

9.  Protective antibody therapy is associated with reduced chemokine transcripts in herpes simplex virus type 1 corneal infection.

Authors:  Y H Su; X T Yan; J E Oakes; R N Lausch
Journal:  J Virol       Date:  1996-02       Impact factor: 5.103

10.  Endocytosis and intracellular processing accompanying transfection mediated by cationic liposomes.

Authors:  D S Friend; D Papahadjopoulos; R J Debs
Journal:  Biochim Biophys Acta       Date:  1996-01-12
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  7 in total

1.  Dysregulation of CXCR3 signaling due to CXCL10 deficiency impairs the antiviral response to herpes simplex virus 1 infection.

Authors:  Todd R Wuest; Daniel J J Carr
Journal:  J Immunol       Date:  2008-12-01       Impact factor: 5.422

Review 2.  Macrophages and cytokines in the early defence against herpes simplex virus.

Authors:  Svend Ellermann-Eriksen
Journal:  Virol J       Date:  2005-08-03       Impact factor: 4.099

3.  Direct application of plasmid DNA containing type I interferon transgenes to vaginal mucosa inhibits HSV-2 mediated mortality.

Authors:  Bobbie Ann Austin; Cassandra M James; Peter Härle; Daniel J J Carr
Journal:  Biol Proced Online       Date:  2006-06-14       Impact factor: 3.244

Review 4.  The role of dendritic cells in immunity against primary herpes simplex virus infections.

Authors:  Sammy Bedoui; Marie Greyer
Journal:  Front Microbiol       Date:  2014-10-21       Impact factor: 5.640

5.  Identification of genes and functional coexpression modules closely related to ulcerative colitis by gene datasets analysis.

Authors:  Jie Zhu; Zheng Wang; Fengzhe Chen; Changhong Liu
Journal:  PeerJ       Date:  2019-11-13       Impact factor: 2.984

Review 6.  Cytokines and chemokines: The vital role they play in herpes simplex virus mucosal immunology.

Authors:  Jacinta B Smith; Jason J Herbert; Naomi R Truong; Anthony L Cunningham
Journal:  Front Immunol       Date:  2022-09-23       Impact factor: 8.786

7.  CD11c controls herpes simplex virus 1 responses to limit virus replication during primary infection.

Authors:  Sariah J Allen; Kevin R Mott; Aziz A Chentoufi; Lbachir BenMohamed; Steven L Wechsler; Christie M Ballantyne; Homayon Ghiasi
Journal:  J Virol       Date:  2011-07-20       Impact factor: 5.103
  7 in total

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