Literature DB >> 1148495

An indirect sympathomimetic effect of burimamide on kitten isolated atria.

A J Hood, J R Smy, D F Weetman.   

Abstract

1. Burimamide (34-1080 muM) caused a concentration-dependent increase in the force and frequency of contraction of kitten isolated atria. 2. Metiamide (467 muM) had no stimulant action on kitten atria and did not modify the effects of burimamide. 3. The atrial stimulation produced by burimamide was reduced by (-)propranolol (34-68 nM) and by cocaine (3 muM). 4. The atrial stimulant effect of burimamide was prevented by pretreatment of kittens with reserpine (1 mg/kg, 24 h before the experiment). 5. It is concluded that burimamide causes atrial stimulation by releasing catecholamines.

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Year:  1975        PMID： 1148495      PMCID： PMC1666327          DOI： 10.1111/j.1476-5381.1975.tb07390.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  9 in total

1.  The effect of reserpine on the catecholamine and adenine nucleotide contents of adrenal gland.

Authors:  W R BURACK; N WEINER; P B HAGEN
Journal:  J Pharmacol Exp Ther       Date:  1960-11       Impact factor: 4.030

2.  The effect on the isolated rabbit heart of vagal stimulation and its modification by cocaine, hexamethonium and ouabain.

Authors:  L M MCEWEN
Journal:  J Physiol       Date:  1956-03-28       Impact factor: 5.182

3.  Definition and antagonism of histamine H 2 -receptors.

Authors:  J W Black; W A Duncan; C J Durant; C R Ganellin; E M Parsons
Journal:  Nature       Date:  1972-04-21       Impact factor: 49.962

4.  Effects in man of histamine H 2 -receptor blockade by burimamide.

Authors:  J H Wyllie; T Hesselbo; J W Black
Journal:  Lancet       Date:  1972-11-25       Impact factor: 79.321

5.  Metiamide--an orally active histamine H2-receptor antagonist.

Authors:  J W Black; W A Duncan; J C Emmett; C R Ganellin; T Hesselbo; M E Parsons; J H Wyllie
Journal:  Agents Actions       Date:  1973-10

6.  The effects of burimamide and metiamide on basal gastric function in the cat.

Authors:  D W Harris; J R Smy; J D Reed; C W Venables
Journal:  Br J Pharmacol       Date:  1975-02       Impact factor: 8.739

7.  The inhibition of noradrenaline uptake by drugs.

Authors:  L L Iversen
Journal:  Adv Drug Res       Date:  1965

8.  A comparison of the anti-arrhythmic actions of I.C.I. 50172 and (--)-propranolol and their effects on intracellular cardiac action potentials and other features of cardiac function.

Authors:  J G Papp; E M Williams
Journal:  Br J Pharmacol       Date:  1969-10       Impact factor: 8.739

9.  A hypothesis concerning the effect of cocaine on the action of sympathomimetic amines.

Authors:  W H MACMILLAN
Journal:  Br J Pharmacol Chemother       Date:  1959-09
  9 in total
  4 in total

1.  Effects of the histamine H2-receptor blocking drugs burimamide and cimetidine on noradrenergic transmission in the isolated aorta of the rabbit and atria of the guinea-pig.

Authors:  M W McCulloch; I C Medgett; M J Rand
Journal:  Br J Pharmacol       Date:  1979-12       Impact factor: 8.739

2.  Inotropic and electrophysiological effects of histamine on human ventricular heart muscle.

Authors:  L Eckel; R W Gristwood; H Nawrath; D A Owen; P Satter
Journal:  J Physiol       Date:  1982-09       Impact factor: 5.182

3.  Effects of midodrine, ST 1059, methoxamine and glycine on spontaneously beating guinea-pig atria.

Authors:  H Pittner
Journal:  Agents Actions       Date:  1976-09

4.  Guanethidine-induced vasodilatation in the rabbit, mediated by endogenous histamine.

Authors:  J A Angus; A Bobik; P I Korner; M T Stoneham
Journal:  Br J Pharmacol       Date:  1978-01       Impact factor: 8.739
  4 in total

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