Literature DB >> 11483993

Transcriptional regulation by the phosphorylation-dependent factor CREB.

B Mayr1, M Montminy.   

Abstract

The transcription factor CREB -- for 'cyclic AMP response element-binding protein' -- functions in glucose homeostasis, growth-factor-dependent cell survival, and has been implicated in learning and memory. CREB is phosphorylated in response to various signals, but how is specificity achieved in these signalling pathways?

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Year:  2001        PMID: 11483993     DOI: 10.1038/35085068

Source DB:  PubMed          Journal:  Nat Rev Mol Cell Biol        ISSN: 1471-0072            Impact factor:   94.444


  880 in total

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