Literature DB >> 11483481

Increased first-contact rates for very-late-onset schizophrenia-like psychosis in African- and Caribbean-born elders.

S J Reeves1, J Sauer, R Stewart, A Granger, R J Howard.   

Abstract

BACKGROUND: Studies have consistently shown a higher incidence of schizophrenia with onset in early adult life in African and Caribbean migrants to the UK. AIMS: To establish the incidence (first-contact rates) of very-late-onset (>60 years) schizophrenia-like psychosis (SLP) in south London and to test the hypothesis that this is higher among African- and Caribbean-born than indigenous elders.
METHOD: We identified all new referrals of SLP to the Maudsley Hospital between 1995 and 2000. Demographic details, including age, ethnicity and electoral ward (address), were obtained from case notes. Incidence was estimated using 1997 census data to determine the denominator population for each ethnic group.
RESULTS: The incidence of SLP was significantly higher in African- and Caribbean-born than indigenous elders: 172.4 per 100,000 population (95% CI=57.9--286.8) in African- and Caribbean-born males and 323.5 per 100,000 population (95% CI 167.8--479.1) in African- and Caribbean-born females. Rates also were increased in elders from other immigrant groups, but the numbers involved were too small to reach accepted levels of significance.
CONCLUSIONS: Large-scale epidemiological studies are needed to determine both the incidence of and the coexistent risk factors for SLP among all elderly migrants, who may constitute a group with high service needs.

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Year:  2001        PMID: 11483481     DOI: 10.1192/bjp.179.2.172

Source DB:  PubMed          Journal:  Br J Psychiatry        ISSN: 0007-1250            Impact factor:   9.319


  6 in total

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Journal:  Soc Psychiatry Psychiatr Epidemiol       Date:  2007-03-12       Impact factor: 4.328

2.  Antipsychotic treatment of very late-onset schizophrenia-like psychosis (ATLAS): a randomised, controlled, double-blind trial.

Authors:  Robert Howard; Elizabeth Cort; Rosie Bradley; Emma Harper; Linda Kelly; Peter Bentham; Craig Ritchie; Suzanne Reeves; Waleed Fawzi; Gill Livingston; Andrew Sommerlad; Sabu Oomman; Ejaz Nazir; Ramin Nilforooshan; Robert Barber; Chris Fox; Ajay Verma Macharouthu; Pranathi Ramachandra; Vivek Pattan; John Sykes; Val Curran; Cornelius Katona; Tom Dening; Martin Knapp; Richard Gray
Journal:  Lancet Psychiatry       Date:  2018-06-04       Impact factor: 27.083

3.  Migration and psychosis: a meta-analysis of incidence studies.

Authors:  Jean-Paul Selten; Els van der Ven; Fabian Termorshuizen
Journal:  Psychol Med       Date:  2019-02-06       Impact factor: 7.723

4.  Allele-specific differences in activity of a novel cannabinoid receptor 1 (CNR1) gene intronic enhancer in hypothalamus, dorsal root ganglia, and hippocampus.

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Review 5.  A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology.

Authors:  John McGrath; Sukanta Saha; Joy Welham; Ossama El Saadi; Clare MacCauley; David Chant
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6.  The Incidence of Nonaffective, Nonorganic Psychotic Disorders in Older People: A Population-based Cohort Study of 3 Million People in Sweden.

Authors:  Jean Stafford; Robert Howard; Christina Dalman; James B Kirkbride
Journal:  Schizophr Bull       Date:  2019-09-11       Impact factor: 9.306

  6 in total

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