Literature DB >> 11483064

Intramolecular 1,3-dipolar cycloaddition strategy for enantioselective synthesis of FR-900482 analogues.

M Kambe1, E Arai, M Suzuki, H Tokuyama, T Fukuyama.   

Abstract

[reaction: see text] Enantioselective synthesis of FR-900482 analogues is described. The key reaction of the synthesis is intramolecular 1,3-dipolar cycloaddition of a highly functionalized nitrile oxide with complete stereo- and regioselectivities to construct the eight-membered benzazocine ring.

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Year:  2001        PMID： 11483064     DOI： 10.1021/ol016243t

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Development of a flexible strategy towards FR900482 and the mitomycins.

Authors:  Barry M Trost; Brendan M O'Boyle; Wildeliz Torres; Michael K Ameriks
Journal:  Chemistry       Date:  2011-05-26       Impact factor: 5.236

Review 2.  Fukuyama reduction, Fukuyama coupling and Fukuyama-Mitsunobu alkylation: recent developments and synthetic applications.

Authors:  Sana Sikandar; Ameer Fawad Zahoor; Shazia Naheed; Bushra Parveen; Kulsoom Ghulam Ali; Rabia Akhtar
Journal:  Mol Divers       Date:  2021-02-11       Impact factor: 2.943

3.  Mitomycins syntheses: a recent update.

Authors:  Jean-Christophe Andrez
Journal:  Beilstein J Org Chem       Date:  2009-07-08       Impact factor: 2.883

Review 4.  The aminoshikimic acid pathway in bacteria as source of precursors for the synthesis of antibacterial and antiviral compounds.

Authors:  Adelfo Escalante; Rubén Mendoza-Flores; Guillermo Gosset; Francisco Bolívar
Journal:  J Ind Microbiol Biotechnol       Date:  2021-12-23       Impact factor: 4.258
  4 in total

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