Literature DB >> 11482761

Effects of Calotropis procera on oestrous cycle and on oestrogenic functionality in rats.

C Circosta1, R Sanogo, F Occhiuto.   

Abstract

Effects of ethanolic and aqueous extracts of Calotropis procera (Ait.) R.Br. roots, have been studied on oestrous cycle and on some parameters of oestrogenic functionality in rats. Both extracts have been shown to interrupt the normal oestrous cycle in 60 and 80%, respectively, of rats treated. The rats exhibited prolonged dioestrous stage of the oestrous cycle with consequent temporary inhibition of ovulation. The contemporary administration of commercial oestro-progestinic preparation exhibited the same effects in 100% of rats treated. However, the extracts have not demonstrated to possess oestrogenic activity when tested in immature female bilaterally ovariectomized rats.

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Year:  2001        PMID： 11482761     DOI： 10.1016/s0014-827x(01)01089-8

Source DB:  PubMed          Journal:  Farmaco        ISSN： 0014-827X


  9 in total

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Review 4.  A review on phytochemical constituents and pharmacological potential of Calotropis procera.

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6.  Cardiac and testicular toxicity effects of the latex and ethanolic leaf extract of Calotropis procera on male albino rats in comparison to abamectin.

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  9 in total

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