P E Wändell1. 1. The Husläkarna i Osteråker Health Centre, Akersberga, Sweden.
Abstract
OBJECTIVE: Five-year mortality in men and women with atrial fibrillation (AF). DESIGN: A follow-up of the medical records of patients with AF registered on September 30, 1993. SETTING: One community health centre in Stockholm County. SUBJECTS: 129 patients (76 men and 53 women). MAIN OUTCOME MEASURES: Observed and expected, age- and sex-standardised, 5-year mortality rates. Significant risk factors by multiple logistic regression. RESULTS: Women had a higher mean age (77.5 vs 72.8 years) and more often suffered from heart failure and hypothyreosis. Five-year mortality rate for men was 30% vs expected 27% in Sweden and 24% in the community; for women it was 43% vs expected 29% (p <0.05) and 23% in the community (p < 0.001), i.e. an excess mortality of 49% and 88%, respectively. Significant factors predicting death by logistic regression among women were: age (odds ratio 1.39, p < 0.001), levothyroxine treatment (odds ratio 27.87, p < 0.05) and diabetes (odds ratio 20.75, p < 0.05). CONCLUSIONS: AF is related to an excess sex- and age-standardised, 5-year mortality in women but not in men, with levothyroxine treatment as one significant factor.
OBJECTIVE: Five-year mortality in men and women with atrial fibrillation (AF). DESIGN: A follow-up of the medical records of patients with AF registered on September 30, 1993. SETTING: One community health centre in Stockholm County. SUBJECTS: 129 patients (76 men and 53 women). MAIN OUTCOME MEASURES: Observed and expected, age- and sex-standardised, 5-year mortality rates. Significant risk factors by multiple logistic regression. RESULTS:Women had a higher mean age (77.5 vs 72.8 years) and more often suffered from heart failure and hypothyreosis. Five-year mortality rate for men was 30% vs expected 27% in Sweden and 24% in the community; for women it was 43% vs expected 29% (p <0.05) and 23% in the community (p < 0.001), i.e. an excess mortality of 49% and 88%, respectively. Significant factors predicting death by logistic regression among women were: age (odds ratio 1.39, p < 0.001), levothyroxine treatment (odds ratio 27.87, p < 0.05) and diabetes (odds ratio 20.75, p < 0.05). CONCLUSIONS:AF is related to an excess sex- and age-standardised, 5-year mortality in women but not in men, with levothyroxine treatment as one significant factor.
Authors: Per Wändell; Axel C Carlsson; Martin J Holzmann; Johan Ärnlöv; Jan Sundquist; Kristina Sundquist Journal: Am J Cardiol Date: 2017-08-30 Impact factor: 2.778
Authors: Thomas Lindow; Josefine Kron; Hans Thulesius; Erik Ljungström; Olle Pahlm Journal: Scand J Prim Health Care Date: 2019-11-04 Impact factor: 2.581