Literature DB >> 11481308

The efficacy of continuous infusion flucloxacillin in home therapy for serious staphylococcal infections and cellulitis.

B P Howden1, M J Richards.   

Abstract

The efficacy and safety of continuous infusion flucloxacillin as home-based treatment was assessed in 62 consecutive patients with proven serious methicillin-susceptible Staphylococcus aureus (MSSA) infections (n = 36) and cellulitis (n = 26). The treatment was well tolerated and resulted in cure or adequate suppression of infection in 27 of 28 (96%) patients in the serious MSSA infection group, and in 24 of 26 (92%) patients in the cellulitis group.

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Year:  2001        PMID： 11481308     DOI： 10.1093/jac/48.2.311

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  8 in total

Review 1.  Continuous versus intermittent intravenous administration of antibacterials with time-dependent action: a systematic review of pharmacokinetic and pharmacodynamic parameters.

Authors:  Sofia K Kasiakou; Kenneth R Lawrence; Nicolaos Choulis; Matthew E Falagas
Journal:  Drugs       Date:  2005       Impact factor: 9.546

2.  Clinical Outcomes With Continuous Nafcillin Infusions in Children.

Authors:  Chad A Knoderer; Lauren C Karmire; Kristen R Nichols
Journal:  J Pediatr Pharmacol Ther       Date:  2017 Jul-Aug

3.  Flucloxacillin alone or combined with benzylpenicillin to treat lower limb cellulitis: a randomised controlled trial.

Authors:  P Leman; D Mukherjee
Journal:  Emerg Med J       Date:  2005-05       Impact factor: 2.740

4.  Population pharmacokinetics at two dose levels and pharmacodynamic profiling of flucloxacillin.

Authors:  Cornelia B Landersdorfer; Carl M J Kirkpatrick; Martina Kinzig-Schippers; Jürgen B Bulitta; Ulrike Holzgrabe; George L Drusano; Fritz Sörgel
Journal:  Antimicrob Agents Chemother       Date:  2007-06-18       Impact factor: 5.191

Review 5.  Outpatient parenteral antimicrobial therapy and antibiotic stewardship: opponents or teammates?

Authors:  Ester Steffens; Charlotte Quintens; Inge Derdelinckx; Willy E Peetermans; Johan Van Eldere; Isabel Spriet; Annette Schuermans
Journal:  Infection       Date:  2018-11-15       Impact factor: 3.553

6.  Setting up an outpatient parenteral antimicrobial therapy (OPAT) unit in Switzerland: review of the first 18 months of activity.

Authors:  C Gardiol; R Voumard; C Cochet; S de Vallière
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2016-02-17       Impact factor: 3.267

7.  Continuous infusion of antibiotics in the critically ill: The new holy grail for beta-lactams and vancomycin?

Authors:  Bruno Van Herendael; Axel Jeurissen; Paul M Tulkens; Erika Vlieghe; Walter Verbrugghe; Philippe G Jorens; Margareta Ieven
Journal:  Ann Intensive Care       Date:  2012-07-02       Impact factor: 6.925

8.  In vivo interactions of continuous flucloxacillin infusion and high-dose oral rifampicin in the serum of 15 patients with bone and soft tissue infections due to Staphylococcus aureus - a methodological and pilot study.

Authors:  Christian Garzoni; Ilker Uçkay; Wilson Belaieff; Dominique Breilh; Domizio Suvà; Elzbieta Huggler; Daniel Lew; Pierre Hoffmeyer; Louis Bernard
Journal:  Springerplus       Date:  2014-06-07
  8 in total

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