Literature DB >> 11481212

Foundations for blockbuster drugs in federally sponsored research.

R B Thompson1.   

Abstract

'Blockbuster' drugs, which are widely prescribed and improve the health of millions, often originate in fundamental laboratory research. An important example of such drugs are the cholesterol-lowering drugs called 'statins', including Zocor, Pravachol, and Lipitor, which millions of people take in the U.S. every year. This short paper outlines the direct and indirect contributions of federally sponsored research to the development of these important drugs.

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Year:  2001        PMID: 11481212     DOI: 10.1096/fj.01-0024lsf

Source DB:  PubMed          Journal:  FASEB J        ISSN: 0892-6638            Impact factor:   5.191


  3 in total

1.  One-step continuous flow synthesis of highly substituted pyrrole-3-carboxylic acid derivatives via in situ hydrolysis of tert-butyl esters.

Authors:  Ananda Herath; Nicholas D P Cosford
Journal:  Org Lett       Date:  2010-10-21       Impact factor: 6.005

2.  Unexpected isocyanide-based three-component bicyclization for the stereoselective synthesis of densely functionalized pyrano[3,4-c]pyrroles.

Authors:  Qian Gao; Wen-Juan Hao; Feng Liu; Shu-Jiang Tu; Shu-Liang Wang; Guigen Li; Bo Jiang
Journal:  Chem Commun (Camb)       Date:  2016-01-18       Impact factor: 6.222

3.  Perceptions and factors affecting pharmaceutical market access: results from a literature review and survey of stakeholders in different settings.

Authors:  Semukaya Sendyona; Isaac Odeyemi; Khaled Maman
Journal:  J Mark Access Health Policy       Date:  2016-09-27
  3 in total

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