| Literature DB >> 1148076 |
Abstract
Experiments are described which demonstrate that dantrolene sodium effectively terminates the syndrome of malignant hyperpyrexia induced in susceptible swine by exposure to halothane. Dantrolene is also shown to block initiation of the syndrome of malignant hyperpyrexia by halothane in MHS swine. Therapeutic use of this drug in patients with anaesthetic-induced malignant hyperpyrexia appears to be indicated.Entities:
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Year: 1975 PMID: 1148076 DOI: 10.1093/bja/47.1.62
Source DB: PubMed Journal: Br J Anaesth ISSN: 0007-0912 Impact factor: 9.166